Results 111 to 120 of about 856,577 (241)
BoreasBasal conditions that facilitate fast ice flow are still poorly understood and their parameterization in ice‐flow models results in high uncertainties in ice‐flow and consequent sea‐level rise projections.
Rebecca Schlegel +5 more
doaj +1 more source
Ice-Shelf Response to Ice-stream Discharge Fluctuations: III. The Effects of Ice-stream Imbalance on the Ross Ice Shelf, Antarctica [PDF]
Journal of Glaciology, 1989 AbstractA numerical simulation of the Ross Ice Shelf, Antarctica, in which discharge from Ice Streams A-E is changed suddenly between extreme states, is used to investigate ice-shelf thickness and flow anomalies generated by ice-stream transience.
openaire +1 more source
Biotechnology and Bioengineering, EarlyView.Lifecycle perspective on cell and gene therapy manufacturing challenges and enabling GMP solutions. ABSTRACT Cell and gene therapies (CGTs) are revolutionizing modern medicine; however, making these advanced medicines scalable and readily available to commercial manufacturers worldwide is a major challenge. The number of approved CGT products continues
Rajath Samaga +2 more
wiley +1 more source
Basal icequakes and sticky spots: Rutford Ice Stream, West Antarctica, near the grounding line
Annals of GlaciologyWe located over one million icequakes that occurred during a 23 day period up-glacier of the grounding line of Rutford Ice Stream (RIS), West Antarctica.
Ian R.J. Lee +7 more
doaj +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT A method to select Escherichia coli citrate synthase variants having reduced activity was developed based initially on the increased generation of acid, observed visually by prolonged color change in the pH indicator bromocresol purple. Five hundred fifty‐two potential variants were isolated and each were cultured on glucose as sole carbon ...
Jeffrey K. Dodelin +3 more
wiley +1 more source
Quantifying subglacial roughness and its link to glacial geomorphology and ice speed [PDF]
, 2013 The shape of subglacial bed topography, termed its roughness, is a recognised control on basal ice-flow. Although glaciologists have observed patterns of variations in ice speed over beds with different roughness values, the strength of this relationship
PRESCOTT, PHILIP,WILLIAM
core
Biotechnology and Bioengineering, EarlyView.ABSTRACT Plant virus‐like particles (VLPs) are promising nanotechnology platforms, but their translation requires purification strategies suitable for large‐scale production. Here, we developed a nuclease‐free downstream process for Physalis mottle virus (PhMV) VLPs expressed in Escherichia coli, combining ammonium sulfate precipitation, low‐pH ...
Sean K. Hsu +3 more
wiley +1 more source
Palaeo-ice streams in the north-eastern Laurentide Ice Sheet
, 2007 This thesis presents a palaeoglaciological study aimed to determine the location, geometry and temporal evolution of palaeo-ice streams of the north-easternmost Laurentide Ice Sheet.
De Angelis, Hernán
core +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT Modified Vaccinia virus Ankara (MVA) is a potent vector for the development of vaccines and novel cancer treatment strategies. Since it is a non‐replicating virus in human recipients, high infective titers are required for therapeutic efficacy.
Linus G. Weber +5 more
wiley +1 more source
Continuous Capture of Recombinant Adeno‐Associated Virus Particles Using Twin‐Column CaptureSMB
Biotechnology and Bioengineering, EarlyView.Continuous twin‐column CaptureSMB enables direct capture of secreted rAAV5 from minimally processed perfusion harvest, bypassing lysis, clarification, and concentration steps. Compared to batch capture, it achieves higher yield (+14.3%), greater productivity (+11.4%), and drastically reduced buffer use (−79.2%), while maintaining critical quality ...
Julia M. Müller +11 more
wiley +1 more source