Results 101 to 110 of about 856,577 (241)

FADS2‐STING Signaling in Sertoli Cells Orchestrates Collagen Deposition and Germ Cell Necroptosis in Idiopathic Non‐Obstructive Azoospermia

Advanced Science, EarlyView.
In Sertoli cells of iNOA testes, downregulation of FADS2 activates STING, promoting collagen deposition and peritubular fibrosis while increasing germ‐cell susceptibility to necroptosis. Supplementation with FADS2‐derived PUFAs (GLA and DHA) inhibits STING, alleviates collagen accumulation, and facilitates the recovery of spermatogenesis.
Jiajing Lin, Hongfei Ke, Xiaomin Li, Man Wu, Zhengyan Wu, Zhiying Huang, Feixue Han, Dejian Pang, Shuyan Chen, Tianwen Peng, Yu Lan, Xin Fu, Yingying Zhang, Hyeon Jeong Lee, Zhicong Chen, Geng An   +15 more
wiley   +1 more source

A Bioengineered Mitochondrial Respiration‐Mimetic Copper‐Based Metal‐Organic Framework Reprogramming Oxidative Phosphorylation to Enhance Tumor Cuproptosis

Advanced Science, EarlyView.
A bioengineered mitochondrial respiration‐mimetic nanoplatform (TC@OMG) renews tumor mitochondrial metabolism to enhance cuproptosis. TC@OMG integrates a copper‐based metal‐organic framework co‐loaded with glucose oxidase and a lactate dehydrogenase inhibitor, and is cloaked with a hybrid membrane derived from tumor cells and plant thylakoids, enabling
Liyang Zhou, Hongpei Deng, Tingli Zheng, Huan Min, Qiwei Tian, Huimin Lin, Jing Ruan, Xianqun Fan   +7 more
wiley   +1 more source

Groundwater dynamics beneath a marine ice sheet [PDF]

The Cryosphere
Sedimentary basins beneath many Antarctic ice streams host substantial volumes of groundwater, which can be exchanged with a “shallow” subglacial hydrological system of till and channelised water.
G. J. Cairns, G. P. Benham, G. P. Benham, I. J. Hewitt   +3 more
doaj   +1 more source

A Closed‐Loop Direct Recycling Process for Prussian White From Scrap and End‐of‐Life Sodium‐Ion Batteries

Advanced Energy Materials, EarlyView.
A closed‐loop direct recycling route for Prussian White sodium‐ion battery cathodes is demonstrated. Ice‐stripped scrap and end‐of‐life electrodes are regenerated via low‐temperature aqueous resodiation (80°C), restoring sodium content, Fe2+ redox chemistry, and structural integrity.
Subha Samanta, Bowen Liu, Dongrui Xie, Joel Cornelio, Wilgner Lima da Silva, Manoj Mayaji Ovhal, Anton Zorin, Peter R. Slater, Emma Kendrick   +8 more
wiley   +1 more source

Dynamics and spatiotemporal variability of ice streams

, 2009
Ice sheets evolve over a wide range of time scales. They grow by snowfall, spread gravitationally, and diminish through melting or iceberg calving at the ice-sheet margin.
Sayag, Roiy
core  

Weather Attention in Online Discourse and Price Uncertainty in Agricultural Futures Markets

Agribusiness, EarlyView.
ABSTRACT Weather is a central determinant of production risk in agricultural markets, but markets respond not only to weather conditions themselves, but also to how those conditions are noticed, framed, and interpreted in public discourse. In this setting, real‐time online weather discussions may shape price uncertainty by influencing how market ...
Mario A. Ortez, Olga Isengildina Massa, Michael Liam Smith, Nicole Olynk Widmar   +3 more
wiley   +1 more source

Programable Acoustic Single‐Cell Manipulation With Model‐Free Machine Learning

Advanced Intelligent Systems, EarlyView.
Closed‐loop control with ultrasound enables precise, noninvasive manipulation of individual cells inside a microfluidic device using a model‐free reinforcement learning‐inspired algorithm, achieving 2D control using a single piezoelectric transducer.
Alexander Edthofer, Guilherme J. Perticarari, Selma Helvelius Bounja, Thierry Baasch   +3 more
wiley   +1 more source

‘Shelter is a Dignity’: Rental Racism, Stress and Housing (In)justice

Australian Journal of Social Issues, EarlyView.
ABSTRACT Australia's private rental sector is in crisis, and culturally and racially minoritised renters face compounded harms through both covert and everyday direct forms of rental racism. Drawing on five community‐based focus groups in Melbourne (n = 37), the paper explores how racism manifests across the rental pathway and how it structures the ...
Erika Martino, Ilan Wiesel, Ang Li, Rebecca Bentley   +3 more
wiley   +1 more source

Adaptive mesh refinement versus subgrid friction interpolation in simulations of Antarctic ice dynamics

Annals of Glaciology, 2016
At least in conventional hydrostatic ice-sheet models, the numerical error associated with grounding line dynamics can be reduced by modifications to the discretization scheme. These involve altering the integration formulae for the basal traction and/or
S. L. Cornford, D. F. Martin, V. Lee, A. J. Payne, E. G. Ng   +4 more
doaj   +1 more source

Impact of Agitation Power Input on Aspergillus oryzae Metabolism: Application of Multi‐Omics on an Industrial Enzyme Fermentation

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The agitation power input substantially impacts the oxygen transfer rate in aerobic fermentation processes. Furthermore, in a carbon‐limited process where the substrate feed rate is controlled by the concentration of dissolved oxygen, the power input will consequently govern the feed rate.
Mariana Albino, Jean‐Marie Mouillon, Gisela Nadal‐Rey, Carina L. Gargalo, Ulrich Krühne, Krist V. Gernaey, Mads O. Albæk   +6 more
wiley   +1 more source