Results 71 to 80 of about 856,577 (241)

Charting Endocrine Progenitors Across Species and Organs

Advanced Science, EarlyView.
Endocrine progenitors give rise to the hormone‐producing cells of the pancreas and intestine. Using single‐cell multiomics and proteomics, this study compares these progenitors across species, systems, and organs, mapping the conserved and species‐specific gene regulatory networks that guide their formation.
Changying Jing, Michael Sterr, Özüm Sehnaz Caliskan, Lama Saber, Nicole Katarina Rogers, Samuel Ogden, Kei Kozawa, Christos Karampelias, Jessica Jaki, Aimée Bastidas‐Ponce, Falk Janos Farkas, Oliver Czarnecki, Osvaldo Rodrigues Pereira, Perla Cota, Valerie Vandenbempt, Diego Balboa, Anika Böttcher, Natalie Krahmer, Mohammad Lotfollahi, Julie B. Sneddon, Heiko Lickert, Mostafa Bakhti   +21 more
wiley   +1 more source

Interplay of grounding-line dynamics and sub-shelf melting during retreat of the Bjørnøyrenna Ice Stream

Scientific Reports, 2018
The Barents Sea Ice Sheet was a marine-based ice sheet, i.e., it rested on the Barents Sea floor during the Last Glacial Maximum (21 ky BP). The Bjørnøyrenna Ice Stream was the largest ice stream draining the Barents Sea Ice Sheet and is regarded as an ...
Michele Petrini, Florence Colleoni, Nina Kirchner, Anna L. C. Hughes, Angelo Camerlenghi, Michele Rebesco, Renata G. Lucchi, Emanuele Forte, Renato R. Colucci, Riko Noormets   +9 more
doaj   +1 more source

Superimposition of ribbed moraines on a palaeo‐ice‐stream bed: implications for ice stream dynamics and shutdown [PDF]

Earth Surface Processes and Landforms, 2008
AbstractThe sediments and landforms preserved on palaeo‐ice‐stream beds can provide important information about their subglacial conditions and flow mechanisms, and the processes accompanying their shutdown. In this paper, detailed observations of an intriguing subglacial landform assemblage of ribbed moraines superimposed on glacial lineations on the ...
Stokes, C.R., Lian, O.B., Tulaczyk, S., Clark, C.D.   +3 more
openaire   +3 more sources

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

An Effector TaCRVP From Tuta Absoluta Oral Secretion Impairs H2O2‐Mediated Plant Defense by Targeting Tomato SlCAT2

Advanced Science, EarlyView.
The Tuta absoluta salivary effector TaCRVP subverts tomato immunity by hijacking host catalase SlCAT2. Through a sophisticated dual mechanism, TaCRVP simultaneously promotes SlCAT2 tetramerization for activation and blocks its SlAdBiL‐mediated degradation for stabilization.
Jianquan Yan, Youdan Zhang, Zhujun Wang, Huatao Tang, Huiping Liu, Zi Chen, Shuai Liu, Jiayi Shi, Lu Peng, Youming Hou   +9 more
wiley   +1 more source

Ice Streams and Grounding Zones of West Antarctica and the Ross Ice Shelf (Abstract)

, 1986
In 1984-85, airborne radar soundings were carried out over West Antarctic ice streams A, B, and C, the neighboring parts of the Ross Ice Shelf, and Crary Ice Rise.
S. Shabtaie, C.R. Bentley
core   +2 more sources

Ice streams in the Laurentide Ice Sheet: a new mapping inventory [PDF]

Journal of Maps, 2014
Rapidly flowing ice streams dominate the drainage of continental ice sheets and are a key component of their mass balance. Due to their potential impact on sea level, their activity in the Antarctic and Greenland Ice Sheets has undergone detailed scrutiny in recent decades.
Margold, M., Stokes, C.R., Clark, C.D., Kleman, J.   +3 more
openaire   +4 more sources

Oral Nanomicelle‐Mediated Sequential Butyrate Production in the Intestine for Ulcerative Colitis and Immunosuppression Treatment

Advanced Science, EarlyView.
After oral administration, inodorous GLU‐BA self‐assembles into nanomicelles in aqueous environments to resist premature gastric adsorption. Upon reaching the intestine, endogenous esterases rapidly cleave the built‐in ester bonds in these nanomicelles to release BA and GLU, with GLU further metabolized by gut microbiota to gradually generate BA ...
Feifei Xin, Zhike Xie, Danyue Zhao, Lin Yang, Yiqun Wan, Zuwei Liu, Situ Xiong, Ying Zhang, Lei Feng, Hao Wan   +9 more
wiley   +1 more source

Basal topographic controls on the stability of the West Antarctic ice sheet: lessons from Foundation Ice Stream

Annals of Glaciology, 2017
Using observations of basal topography, ice thickness and modern accumulation rates, we use theory and a dynamic flowline model to examine the sensitivity of Antarctica's Foundation Ice Stream to changes in sea level, accumulation and buttressing at the ...
Kathleen Huybers, Gerard Roe, Howard Conway   +2 more
doaj   +1 more source