Results 61 to 70 of about 2,271,419 (323)

A weekly Arctic sea-ice thickness data record from merged CryoSat-2 and SMOS satellite data

, 2017
. Sea-ice thickness on a global scale is derived from different satellite sensors using independent retrieval methods. Due to the sensor and orbit characteristics, such satellite retrievals differ in spatial and temporal resolution as well as in the ...
R. Ricker, S. Hendricks, L. Kaleschke, X. Tian-Kunze, Jennifer King, C. Haas   +5 more
semanticscholar   +1 more source

New Last Glacial Maximum ice thickness constraints for the Weddell Sea Embayment, Antarctica

The Cryosphere, 2019
. We describe new Last Glacial Maximum (LGM) ice thickness constraints for three locations spanning the Weddell Sea Embayment (WSE) of Antarctica. Samples collected from the Shackleton Range, Pensacola Mountains, and the Lassiter Coast constrain the LGM ...
K. Nichols, B. Goehring, G. Balco, Joanne S. Johnson, A. Hein, Claire Todd   +5 more
semanticscholar   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Influence of Ice Growth Mode on the Ice Thickness and Shape Prediction of Two-Dimensional Airfoil

Aerospace
Computational results of aircraft icing and predictions of ice shape are not only determined by the solutions of air-supercooled droplet two-phase flow and icing thermodynamic models of surface water film, but are also influenced by the growth mode of ...
Xiaobin Shen, Jingyu Zhao, Zekun Ye, Huanfa Wang, Guiping Lin   +4 more
doaj   +1 more source

Ice Thickness and Bed Elevation of the Northern and Southern Patagonian Icefields

Geophysical Research Letters, 2019
The Northern and Southern Patagonian Icefields are the largest ice masses in the Southern Hemisphere outside Antarctica, but their ice volume and bed topography are poorly known.
R. Millan, E. Rignot, A. Rivera, V. Martineau, J. Mouginot, R. Zamora, J. Uribe, G. Lenzano, B. D. Fleurian, Xiaoxiao Li, Y. Gim, D. Kirchner   +11 more
semanticscholar   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Improvement and Sensitivity Analysis of Thermal Thin-Ice Thickness Retrievals [PDF]

, 2012
Considering the sea ice decline in the Arctic during the last decades, polynyas are of high research interest since these features are core areas of new ice formation.
Adams, Susann, Heinemann, Günther, Krumpen, Thomas, Schroeder, David   +3 more
core   +1 more source

Assessing the Impact of Lead and Floe Sampling on Arctic Sea Ice Thickness Estimates from Envisat and CryoSat‐2

Journal of Geophysical Research: Oceans, 2019
Multidecadal observations of sea ice thickness, in addition to those available for extent, are key to understanding long ‐ term variations and trends in the amount of Arctic sea ice. The European Space Agency's Envisat (2002 – 2010) and CryoSat ‐ 2 (2010
R. Tilling, A. Ridout, A. Shepherd
semanticscholar   +1 more source

Monitoring Sea Ice Thickness Using GNSS-Interferometric Reflectometry

IEEE Geoscience and Remote Sensing Letters, 2022
Abstract This letter presents the analysis of frozen sea surface properties using low-cost and low-complexity terrestrial global navigation satellite system (GNSS) receivers. Monitoring sea ice thickness and the mean sea level (MSL) of the frozen sea are performed using the interference frequency obtained by the GNSS interference pattern (IP) technique.
Ankit Regmi, Marko E. Leinonen, Aarno Parssinen, Markus Berg   +3 more
openaire   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source