Results 61 to 70 of about 2,510,664 (339)

Including debris cover effects in a distributed model of glacier ablation [PDF]

open access: yes, 2012
Distributed glacier melt models generally assume that the glacier surface consists of bare exposed ice and snow. In reality, many glaciers are wholly or partially covered in layers of debris that tend to suppress ablation rates.
Andersen   +48 more
core   +1 more source

Sea-ice thickness measurement based on the dispersion of ice swell

open access: yesThe Journal of the Acoustical Society of America, 2012
The dispersion of flexural waves propagating in the Arctic sea ice cover is exploited in order to locally measure the ice thickness. The observed dispersion, for waves filtered in the 4–20 s period interval, at up to 4 broad-band seismometers deployed in Spring 2007 near the North Pole, is compared to a parameterized model that accounts for a complex ...
Marsan, David   +3 more
openaire   +5 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Influence of Ice Growth Mode on the Ice Thickness and Shape Prediction of Two-Dimensional Airfoil

open access: yesAerospace
Computational results of aircraft icing and predictions of ice shape are not only determined by the solutions of air-supercooled droplet two-phase flow and icing thermodynamic models of surface water film, but are also influenced by the growth mode of ...
Xiaobin Shen   +4 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Modeling the thermodynamics of a sea ice thickness distribution: 1. Sensitivity to ice thickness resolution [PDF]

open access: yesJournal of Geophysical Research: Oceans, 1997
A one‐dimensional ice thickness distribution model is presented to determine the minimum number of ice thicknesses necessary to resolve the area‐averaged annual cycles of ice thickness and turbulent fluxes. The baseline case includes 40 ice thickness categories; ice thickness and area, meltwater ponds, ice salinity and age, snow cover, and surface ...
J. L. Schramm   +3 more
openaire   +1 more source

A weekly Arctic sea-ice thickness data record from merged CryoSat-2 and SMOS satellite data

open access: yes, 2017
. Sea-ice thickness on a global scale is derived from different satellite sensors using independent retrieval methods. Due to the sensor and orbit characteristics, such satellite retrievals differ in spatial and temporal resolution as well as in the ...
R. Ricker   +5 more
semanticscholar   +1 more source

Ice Thickness and Bed Elevation of the Northern and Southern Patagonian Icefields

open access: yesGeophysical Research Letters, 2019
The Northern and Southern Patagonian Icefields are the largest ice masses in the Southern Hemisphere outside Antarctica, but their ice volume and bed topography are poorly known.
R. Millan   +11 more
semanticscholar   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Arctic sea ice variation in the Northwest Passage in 1979–2017 and its response to surface thermodynamics factors

open access: yesAdvances in Climate Change Research, 2021
Sea ice conditions in the Canadian Arctic Archipelago (CAA) play a key role in the navigation of the Northwest Passage (NWP). Limited by observed sea ice thickness data, the research of temporal and spatial variation of sea ice in the NWP is insufficient.
Xin-Yi Shen   +7 more
doaj   +1 more source

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