Results 211 to 220 of about 4,378,278 (308)

Modelling Future Evolution of the Antarctic Ice Sheet With Explainable Machine Learning. [PDF]

J R Soc N Z
Maddigan P, Nguyen BH, Siew PYF, Xue B, Golledge N, Zhang M.   +5 more
europepmc   +1 more source

p300‐Mediated H3K18 Lactylation Drives Radiation‐Induced Pulmonary Fibrosis via VIRMA‐Dependent m6A Modification of GATA3

Advanced Science, EarlyView.
Radiation triggers glycolytic reprogramming in alveolar epithelial type II cells, causing pathological lactate accumulation. This metabolic stress drives p300‐mediated H3K18 lactylation at the VIRMA promoter, activating transcription. Elevated VIRMA enriches m6A on GATA3 mRNA, which YTHDF1 stabilizes, ultimately driving epithelial–mesenchymal ...
Junxuan Yi, Mingwei Wang, Duo Yu, Mingqi Zhao, Xinyan Wang, Shiqi Li, Xiaowen Han, Wei Wei, Shunzi Jin   +8 more
wiley   +1 more source

Modeling of the electrostatic field generated by horizontal current sources in a sea-ice-covered four-layer medium. [PDF]

Sci Rep
Chen X, Sun Z, Jiang C, Zhu K, Li M, Jiang R, Yang W, Yan K, Du Y.   +8 more
europepmc   +1 more source

A Cascaded DNA Nanocircuit for Multi‐Signal‐Responsive Precision siRNA Delivery in Cancer Therapy

Advanced Science, EarlyView.
A cascaded dual‐AND logic DNA nanocircuit is engineered to respond to three tumor‐specific signals in a sequential manner: extracellular acidic pH, membrane‐overexpressed nucleolin (NCL), and intracellular glutathione (GSH). This programmable system selectively releases siPARP1 in glioblastoma (GBM), effectively silencing PARP1 and reversing TMZ ...
Yan Zhao, Yufei Lan, Min‐Goo Lee, Jinjun He, Yueran Pan, Eunji Kim, Xin Fu, Sungwook Jung, Wanxia Lu, Jinyue Fan, Haoxiang Chen, Yuanbo Zhao, Yuling Xu, Jong Seung Kim, Chao Zhang   +14 more
wiley   +1 more source

Probing the structure of D₂O ice layers on ALD-grown ZrO₂, Al₂O₃ and TiO₂ thin films by sum frequency generation (SFG) spectroscopy.

Faraday Discuss
Li X, Gross S, Haunold T, Jang MH, Zukalova M, Jindra M, Olszówka JE, Lei Y, Vajda Š, Rupprechter G.   +9 more
europepmc   +1 more source

Conversion-Type Anodes: Challenges, Mitigation Strategies, and Evaluation Guidelines. [PDF]

Small
Hwang S, Yoon WS.
europepmc   +1 more source

Atmospheric Water Harvesting Through Polymer Hydrogel Sorbents: Materials Chemistry, Design Strategies, and Applications

Advanced Science, EarlyView.
Polymer‐based hydrogels have emerged as promising materials for atmospheric water harvesting (AWH) due to their high water affinity, tunable network structure, and excellent moisture adsorption‐desorption performance. Functional hydrogel systems enable efficient water capture and controlled release under low‐energy conditions, offering a sustainable ...
Swagata Datta, Sushmit Sen, Nilanjan Dey, Amrita Chatterjee, Ananya Sadhu, Sudipta Sarkar, Pradip K. Maji   +6 more
wiley   +1 more source

Simple and robust aqueous sheet jets in vacuum. [PDF]

IUCrJ
Konold PE, Ansari A, Westphal D, Adams P, Letrun R, Valerio J, Bielecki J, Alvarez RC, Bódizs S, Dörner K, Ducrocq G, Grunewald L, Kharitonov K, Kim C, Kloos M, Králová A, Larkiala T, Maihöfer M, Manatou D, Mehlig R, Melo DVM, Meszaros P, Monrroy L, Sato T, Schubert R, Smyth P, Sobolev E, Trost F, de Wijn R, Worbs L, Yenupuri TV, You T, Schulz J, Bean R, Ayyer K, Martin MAD, Kirst H, Grubmüller H, Westenhoff S, Kirian RA, Maia FRNC.   +40 more
europepmc   +1 more source

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

Advanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang, Zitong Huang, Yu Tao, Yunmei Zhang, Yufang Sun, Dongsheng Jiang, Weiwei Lu, Fuhai Ji, Gang Chen, Min Xu, Yuan Zhang, Jin Tao   +11 more
wiley   +1 more source

Ultrahigh pressure phase transition in ice. [PDF]

Nat Mater
Osmond I, Kuzovnikov MA, Lewis DA, Shuttleworth HA, Marqueño T, Dixon MJ, Robertson CEA, Cherepnalkoski V, Wang B, Hermann A, Peña-Alvarez M, Howie RT.   +11 more
europepmc   +1 more source