Results 61 to 70 of about 69,716 (313)

Ice Crystal Terminal Velocities [PDF]

Journal of the Atmospheric Sciences, 1972
Terminal velocities of different ice crystal forms were calculated, using the most recent ice crystal drag coefficients, aspect ratios, and densities. The equations derived were primarily for use in calculating precipitation rates by sampling particles with an aircraft in cirrus clouds, and determining particle size in cirrus clouds by Doppler radar ...
openaire   +1 more source

Improving the spatial distribution of modeled Arctic sea ice thickness

, 2005
The spatial distribution of ice thickness/draft in the Arctic Ocean is examined using a sea ice model. A comparison of model predictions with submarine observations of sea ice draft made during cruises between 1987 and 1997 reveals that the model has the
Laxon, SW, Miller, PA, Feltham, DL, Laxon, S. W., Feltham, D. L., Miller, P. A.   +5 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

The Statistical Properties of Sea Ice Velocity Fields

Journal of Climate, 2017
By arguing that the surface pressure field over the Arctic Ocean can be treated as an isotropic, stationary, homogeneous, Gaussian random field, Thorndike estimated a number of covariance functions from two years of data (1979 and 1980). Given the active interest in changes of general circulation quantities and indices in the polar regions during the ...
Agarwal, Sahil, Wettlaufer, John S.
openaire   +2 more sources

balance velocities of the Greenland Ice Sheet [PDF]

Geophysical Research Letters, 1997
We present a map of balance velocities for the Greenland ice sheet. The resolution of the underlying DEM, which was derived primarily from radar altimetery data, yields far greater detail than earlier balance velocity estimates for Greenland. The velocity contours reveal in striking detail the location of an ice stream in northeastern Greenland, which ...
Ian Joughin, Mark Fahnestock, Simon Ekholm, Ron Kwok   +3 more
openaire   +1 more source

Experimental and numerical modeling of high speed ice impact onto rigid target [PDF]

, 2015
The core goal of this research is to develop an ice impact modelling methodology for ice impact on aircraft structures. The main current limitation of ice impact analysis is the ice constitutive model, so this research is focussed on the assessment and ...
Heng, Fangming
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Local scour around a bridge pier under ice-jammed flow condition – an experimental study

Journal of Hydrology and Hydromechanics, 2021
The appearance of an ice jam in a river crucially distorts local hydrodynamic conditions including water level, flow velocity, riverbed form and local scour processes.
Wang Jun, Hou Zhixing, Sun Hongjian, Fang Bihe, Sui Jueyi, Karney Bryan   +5 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Velocity Anomaly of Campbell Glacier, East Antarctica, Observed by Double-Differential Interferometric SAR and Ice Penetrating Radar

Remote Sensing, 2021
Regional changes in the flow velocity of Antarctic glaciers can affect the ice sheet mass balance and formation of surface crevasses. The velocity anomaly of a glacier can be detected using the Double-Differential Interferometric Synthetic Aperture Radar
Hoonyol Lee, Heejeong Seo, Hyangsun Han, Hyeontae Ju, Joohan Lee   +4 more
doaj   +1 more source