Results 61 to 70 of about 23,695 (309)

Middle and Late Pleistocene environmental history of the Marsworth area, south-central England [PDF]

, 2014
To elucidate the Middle and Late Pleistocene environmental history of south-central England, we report the stratigraphy, sedimentology, palaeoecology and geochronology of some deposits near the foot of the Chiltern Hills scarp at Marsworth ...
Adamiec, Andrew Currant, Andrews, Avery, Ballantyne, Barrow, Bascomb, Bates, Bates, Bates, Bowen, Bowen, Bowen, Bowen, Bowen, Bowen, Bowen, Bowen, Bowen, Bridgland, Candy, Candy, Candy, Canti, Christopher P. Green, Clark, Clayden, Coope, Coope, Currant, Danielle C. Schreve, David H. Keen, David Parish, David Q. Bowen, de Deckker, de Rouffignac, EPICA community members, Evans, Evans, Evans, Galbraith, Gibbard, Gibbard, Gibbard, Gibbard, Green, Green, Gregory, Griffiths, Hamblin, Harmer, Harris, Hill, Hiltermann, Holyoak, Horton, Huntley, Ian Candy, Jarvis, John A. Catt, John G. Evans, Jones, Jones, Jouzel, Julian B. Murton, Kandiano, Kaufman, Keen, Keen, Keen, Keen, Keen, Kerney, Kerney, Kirsty Penkman, Linda L. York, Lisiecki, Lister, Lister, Loveday, Maddy, Markey, McManus, Meijer, Meisch, Mejdahl, Michael P. Kerney, Michael R. Frogley, Miller, Miller, Morgan, Mortimore, Murray, Murray, Murray, Murton, Murton, Murton, Murton, Murton, Murton, Oakley, Oches, Pawley, Penkman, Penkman, Penkman, Penkman, Penkman, Peter Worsley, Phillip S. Toms, Preece, Preece, Prescott, Robinson, Rose, Rousseau, Schreve, Sheila Taylor, Shephard-Thorn, Shephard-Thorn, Sherlock, Sherlock, Soil Survey of England and Wales, Sparks, Stathoplos, Straw, Sumbler, Sumbler, Sykes, Wehmiller, Wenban-Smith, Whiteman, Williams, Williams, Williams, Worsley, Zimmerman   +137 more
core   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Nonlinear thermal and moisture response of ice-wedge polygons to permafrost disturbance increases heterogeneity of high Arctic wetland [PDF]

Biogeosciences, 2016
Low-center polygonal terrains with gentle sloping surfaces and lowlands in the high Arctic have a potential to retain water in the lower central portion of ice-wedge polygons and are considered high-latitude wetlands.
E. Godin, D. Fortier, E. Lévesque
doaj   +1 more source

GeoTechnical Investigations for the Dalton Highway Innovation Project As A Case Study of the Ice-Rich Syngenetic Permafrost [PDF]

, 2010
INE/AUTC 11 ...
Dillon, Matthew, Kanevskiy, Mikhail, O’Donnell, Jonathan, Shur, Yuri, Stephani, Eva   +4 more
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Effects of ice-wedge degradation and warming on Arctic tundra vegetation across a climatic gradient using a nitrogen-based model

Arctic, Antarctic, and Alpine Research
Ice-wedge polygons in Arctic tundra landscapes influence hydrology, nutrients, thermal regimes, and vegetation. Ice-wedges are particularly vulnerable to warming events, and widespread degradation has been observed in recent decades.
Kelcy Kent, Howard E. Epstein, Lindsay Grose, Mark Torre Jorgenson, Anna Liljedahl   +4 more
doaj   +1 more source

Degradation of Arable Soils in Central Yakutia: Negative Consequences of Global Warming for Yedoma Landscapes

Frontiers in Earth Science, 2021
Global warming, which is especially intensive (up to 0.08°C yr−1) in permafrost area of Central Yakutia, has dramatic consequences for scarce arable land resources in this region.
Roman Desyatkin, Nikolai Filippov, Alexey Desyatkin, Dmitry Konyushkov, Sergey Goryachkin   +4 more
doaj   +1 more source

Fossil Ice Wedges in Hampshire [PDF]

Nature, 1966
THREE large fossil ice wedges have been discovered in a coastal section exposed at Highcliffe in Hampshire (M.R. 215931). They are to be found within the Plateau Gravel in the uppermost part of the cliff at about 100′ O.D. Here 2.4 m of gravels rest on Barton Beds, at this point consisting of an impermeable glauconitic clay. On top of the gravels is an
openaire   +1 more source

Holocene thermokarst and pingo development in the Kolyma Lowland (NE Siberia) [PDF]

, 2018
Ground ice and sedimentary records of a pingo exposure reveal insights into Holocene permafrost, landscape and climate dynamics. Early to mid‐Holocene thermokarst lake deposits contain rich floral and faunal paleoassemblages, which indicate lake ...
Bobrov, Anatoly, Fritz, Michael, Günther, Frank, Matthes, Heidrun, Meyer, Hanno, Nazarova, Larisa, Opel, Thomas, Palagushkina, Olga, Pogosyan, Lilit, Savelieva, Larisa, Schirrmeister, Lutz, Syrykh, Liudmila, Wetterich, Sebastian   +12 more
core   +2 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source