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Liquid biopsy in gastrointestinal oncology: clinical applications and translational integration of ctDNA, CTCs, and sEVs. [PDF]
Palieri R +12 more
europepmc +1 more source
Exploring Microbial Dark Matter for the Discovery of Novel Natural Products: Characteristics, Abundance Challenges and Methods. [PDF]
Alanzi AR.
europepmc +1 more source
Metabolic engineering approaches for the biosynthesis of antibiotics. [PDF]
Yook G, Nam J, Jo Y, Yoon H, Yang D.
europepmc +1 more source
Synthetic Biology of Natural Products Engineering: Recent Advances Across the Discover-Design-Build-Test-Learn Cycle. [PDF]
Foldi J +3 more
europepmc +1 more source
Isolation and typing techniques for circulating tumor cells. [PDF]
Wu S, Rong S, He A, Xia Y, Xu F.
europepmc +1 more source
Allele-specific epigenetic events regulate the expression of specific genes such as tumor suppressor genes. Methods to biochemically identify epigenetic regulators remain limited. Here, we used insertional chromatin immunoprecipitation (iChIP) to address this issue.
Hodaka Fujii
exaly +4 more sources
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FACS-iChip: a high-efficiency iChip system for microbial ‘dark matter’ mining
Marine Life Science and Technology, 2020The isolation chip method (iChip) provides a novel approach for culturing previously uncultivable microorganisms; this method is currently limited by the user being unable to ensure single-cell loading within individual wells. To address this limitation, we integrated flow cytometry-based fluorescence-activated cell sorting with a modified iChip (FACS ...
Erinne Stirling, Jianming Xu, Bin Ma
exaly +3 more sources
Teixobactin, the first of a new class of antibiotics discovered by iChip technology? [PDF]
Teixobactin is a recently described antibiotic of a new class produced by a hitherto undescribed soil microorganism (provisionally named Eleftheria terrae). It was isolated with a new tool, the iChip, that allowed the environmental bacterium to grow and for the antibiotic it produced to be isolated and subsequently identified.
Laura Piddock
exaly +4 more sources
Methods in Molecular Biology, 2022
The ability to isolate and analyze rare circulating tumor cells (CTCs) holds the potential to increase our understanding of cancer evolution and allows monitoring of disease and therapeutic responses through a relatively non-invasive blood-based biopsy.
Avanish Mishra, Risa Burr, Jon Edd
exaly +3 more sources
The ability to isolate and analyze rare circulating tumor cells (CTCs) holds the potential to increase our understanding of cancer evolution and allows monitoring of disease and therapeutic responses through a relatively non-invasive blood-based biopsy.
Avanish Mishra, Risa Burr, Jon Edd
exaly +3 more sources

