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Liquid biopsy in gastrointestinal oncology: clinical applications and translational integration of ctDNA, CTCs, and sEVs. [PDF]

open access: yesOncol Rev
Palieri R   +12 more
europepmc   +1 more source

i C h IP ‐ SILAC analysis identifies epigenetic regulators of C p G methylation of the p16 INK4A gene

open access: yesFEBS Letters
Allele-specific epigenetic events regulate the expression of specific genes such as tumor suppressor genes. Methods to biochemically identify epigenetic regulators remain limited. Here, we used insertional chromatin immunoprecipitation (iChIP) to address this issue.
Hodaka Fujii
exaly   +4 more sources
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FACS-iChip: a high-efficiency iChip system for microbial ‘dark matter’ mining

Marine Life Science and Technology, 2020
The isolation chip method (iChip) provides a novel approach for culturing previously uncultivable microorganisms; this method is currently limited by the user being unable to ensure single-cell loading within individual wells. To address this limitation, we integrated flow cytometry-based fluorescence-activated cell sorting with a modified iChip (FACS ...
Erinne Stirling, Jianming Xu, Bin Ma
exaly   +3 more sources

Teixobactin, the first of a new class of antibiotics discovered by iChip technology? [PDF]

open access: yesJournal of Antimicrobial Chemotherapy, 2015
Teixobactin is a recently described antibiotic of a new class produced by a hitherto undescribed soil microorganism (provisionally named Eleftheria terrae). It was isolated with a new tool, the iChip, that allowed the environmental bacterium to grow and for the antibiotic it produced to be isolated and subsequently identified.
Laura Piddock
exaly   +4 more sources

Negative-Selection Enrichment of Circulating Tumor Cells from Peripheral Blood Using the Microfluidic CTC-iChip

Methods in Molecular Biology, 2022
The ability to isolate and analyze rare circulating tumor cells (CTCs) holds the potential to increase our understanding of cancer evolution and allows monitoring of disease and therapeutic responses through a relatively non-invasive blood-based biopsy.
Avanish Mishra, Risa Burr, Jon Edd
exaly   +3 more sources

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