Results 101 to 110 of about 5,904 (262)
Allergy, EarlyView.ABSTRACT These updated EAACI guidelines aim to standardize skin testing methodologies for both immediate and non‐immediate drug hypersensitivity reactions. For immediate reactions, the optimal testing window is 4–6 weeks post‐reaction; whereas beyond 6 months, false‐negative results increase.
Annick Barbaud +14 more
wiley +1 more source
Nomenclature on Immune‐Mediated Drug Reactions: An EAACI Position Paper
Allergy, EarlyView.ABSTRACT Over the past several decades, there have been significant advances in our understanding of both immunological and pharmacological mechanisms of adverse drug reactions (ADRs). Immune‐mediated drug reactions (IMDRs) represent a small proportion of ADRs and are caused by a pathological activation of the immune system or inflammatory pathways ...
Maria J. Torres +19 more
wiley +1 more source
ANZ Journal of Surgery, EarlyView.The preoperative Multi‐Domain Risk Stratification model effectively stratified operative risk in older adults undergoing cholecystectomy for acute cholecystitis, predicting prolonged hospital stay, medical complications, and Medical Emergency Team calls, supporting its role in comprehensive preoperative risk assessment and perioperative decision‐making.
Kate Wylde +6 more
wiley +1 more source
Acta Obstetricia et Gynecologica Scandinavica, EarlyView.In this retrospective cohort study, the vacuum‐assisted hemorrhage‐control device for refractory postpartum hemorrhage, implemented within an E‐MOTIVE and ROTEM‐guided protocol, was associated with reduced transfusion requirements, decreased device indwelling time, fewer high‐dependency admissions, and a shorter duration of hospital stay compared to ...
Kelvin Z. X. Lee +13 more
wiley +1 more source
Artificial Organs, EarlyView.Preventable geometric failure modes, such as outflow graft kinking and inflow malposition, frequently cause HeartMate 3 dysfunction. This study identifies these complications as key drivers of device‐related morbidity, highlighting the importance of optimized surgical positioning to ensure long‐term device performance and improved clinical outcomes ...
Ali Saad Merzah +17 more
wiley +1 more source
Acta Paediatrica, EarlyView.ABSTRACT Aim To compare outcomes of planned home or freestanding midwifery unit (FMU) with obstetric unit births in high‐income countries. Methods We conducted a systematic review and meta‐analysis of systematic reviews, randomised controlled trials, cohort studies, case series, and case reports.
Carolina Herding +12 more
wiley +1 more source
Birth, EarlyView.ABSTRACT The 2025 revision of Ireland's midwifery education standards marks the first comprehensive update since 2012 and includes an important step forward in acknowledging trans and gender diverse (TGD) people as recipients of midwifery care. However, despite this progress, the standards remain constrained by gender‐exclusive language and a lack of ...
John P. Gilmore +8 more
wiley +1 more source
New biosensors and transgenic mice for multiplex cGMP imaging
British Journal of Pharmacology, EarlyView.Background and Purpose Cyclic guanosine monophosphate (cGMP) is a versatile second messenger that is important for human (patho‐)physiology and pharmacotherapy. Live‐cell imaging of cGMP with biosensors allows to elucidate its spatiotemporal dynamics in real time under close‐to‐native conditions. However, to monitor two separate cGMP pools or cGMP/cAMP
Markus Wolters +6 more
wiley +1 more source