Blocking nuclear receptor Nr4a3 unlocks the senescence barrier to promote direct cardiac reprogramming. [PDF]
Liu M +12 more
europepmc +1 more source
Psychosocial Determinants of Pain in Muscle Biopsy
ABSTRACT Introduction/Aims Open muscle biopsy (OMB) is a key diagnostic tool for neuromuscular diseases, though patients often worry about risks and discomfort. This study aimed to assess pain during and after OMB, factors influencing pain perception, and adverse events.
Beatrice Labella +11 more
wiley +1 more source
Dexamethasone Suppresses Already Low Estrogen Receptor Levels in Meningiomas. [PDF]
Hugh JC, Haddon LSJ, Githaka JM.
europepmc +1 more source
Integrated analysis with iCM‐SANS, SAXS and MD simulations for dynamics of multi‐domain proteins
Segmental deuteration, combined with inverse contrast‐matching small‐angle neutron scattering (iCM‐SANS) and small‐angle X‐ray scattering (SAXS), provides structural constraints that improve discrimination of conformation ensembles of multi‐domain proteins derived from molecular dynamics (MD) simulations.Multi‐domain proteins (MDPs) adopt diverse ...
Aya Okuda +10 more
wiley +1 more source
Purslane (Portulaca oleracea L.) Extract Alleviates Atherosclerosis in ApoE<sup>-/-</sup> Mice. [PDF]
Wang Y +5 more
europepmc +1 more source
Microbial communities in a Mediterranean subterranean estuary show spatially structured nitrogen‐cycling potential across hydrochemical zones. Microbial properties, more than environmental variables, predict NO2− and NH4+ concentrations, highlighting their key role in controlling nitrogen transformations prior to submarine groundwater discharge ...
Daniel Romano‐Gude +13 more
wiley +1 more source
Nobiletin Protects Endothelial Function in High-Fat Diet-Induced Obese Mice Through Activation of 5' Adenosine Monophosphate-Activated Protein Kinase. [PDF]
Deng Q +6 more
europepmc +1 more source
ctDNA Detection of Polyclonal KRAS Resistance in Adagrasib‐Treated NSCLC
Longitudinal ctDNA monitoring by ddPCR and targeted NGS in an adagrasib‐treated KRASG12C mutant NSCLC patient revealed the emergence of three new KRAS mutations (G12D, G13D, Q61H), indicating polyclonal resistance, approximately 10 weeks before any radiologic progression by RECIST 1.1.
Marion Caumeil +5 more
wiley +1 more source
Pharmacovigilance analysis of iodinated contrast media related respiratory adverse effects based on the FDA adverse event reporting system. [PDF]
Rui Y +7 more
europepmc +1 more source
ABSTRACT The aim of this study was to synthesize evidence on the influence of Enterococcus faecalis on endodontic treatment failure and strategies for its elimination. This study followed the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) guidelines and was registered in PROSPERO (CRD420251022741).
Francine Santos Fernandes de Lima +1 more
wiley +1 more source

