Results 171 to 180 of about 5,904 (262)

Blocking nuclear receptor Nr4a3 unlocks the senescence barrier to promote direct cardiac reprogramming. [PDF]

open access: yesSci Adv
Liu M   +12 more
europepmc   +1 more source

Psychosocial Determinants of Pain in Muscle Biopsy

open access: yesMuscle &Nerve, Volume 74, Issue 2, Page 383-389, August 2026.
ABSTRACT Introduction/Aims Open muscle biopsy (OMB) is a key diagnostic tool for neuromuscular diseases, though patients often worry about risks and discomfort. This study aimed to assess pain during and after OMB, factors influencing pain perception, and adverse events.
Beatrice Labella   +11 more
wiley   +1 more source

Integrated analysis with iCM‐SANS, SAXS and MD simulations for dynamics of multi‐domain proteins

open access: yesJournal of Applied Crystallography, Volume 59, Issue 4, Page 1270-1281, August 2026.
Segmental deuteration, combined with inverse contrast‐matching small‐angle neutron scattering (iCM‐SANS) and small‐angle X‐ray scattering (SAXS), provides structural constraints that improve discrimination of conformation ensembles of multi‐domain proteins derived from molecular dynamics (MD) simulations.Multi‐domain proteins (MDPs) adopt diverse ...
Aya Okuda   +10 more
wiley   +1 more source

Spatial Partitioning of Microbial Functional Potential Suggests Complex Nitrogen Cycling in a Subterranean Estuary

open access: yesEnvironmental Microbiology, Volume 28, Issue 8, August 2026.
Microbial communities in a Mediterranean subterranean estuary show spatially structured nitrogen‐cycling potential across hydrochemical zones. Microbial properties, more than environmental variables, predict NO2− and NH4+ concentrations, highlighting their key role in controlling nitrogen transformations prior to submarine groundwater discharge ...
Daniel Romano‐Gude   +13 more
wiley   +1 more source

ctDNA Detection of Polyclonal KRAS Resistance in Adagrasib‐Treated NSCLC

open access: yesThoracic Cancer, Volume 17, Issue 15, August 2026.
Longitudinal ctDNA monitoring by ddPCR and targeted NGS in an adagrasib‐treated KRASG12C mutant NSCLC patient revealed the emergence of three new KRAS mutations (G12D, G13D, Q61H), indicating polyclonal resistance, approximately 10 weeks before any radiologic progression by RECIST 1.1.
Marion Caumeil   +5 more
wiley   +1 more source

Enterococcus faecalis and Endodontic Treatment Failure: A Qualitative Systematic Review of Its Role and Elimination Strategies

open access: yesAustralian Endodontic Journal, Volume 52, Issue 2, Page 585-605, August 2026.
ABSTRACT The aim of this study was to synthesize evidence on the influence of Enterococcus faecalis on endodontic treatment failure and strategies for its elimination. This study followed the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) guidelines and was registered in PROSPERO (CRD420251022741).
Francine Santos Fernandes de Lima   +1 more
wiley   +1 more source

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