Results 191 to 200 of about 15,787 (297)

Optimising Connectivity in Deep‐Sea MPA Networks for Nephrops norvegicus Recovery in NW Mediterranean Sea

open access: yesEcology and Evolution, Volume 16, Issue 10, October 2026.
In the NW Mediterranean, where the Norway lobster (Nephrops norvegicus) is both ecologically and economically important, larval connectivity in an existing network of Fishery No‐Take Zones was estimated using Lagrangian transport simulation informed by species‐specific habitat models.
Morane Clavel‐Henry   +5 more
wiley   +1 more source

Effect of Hyaluronic Acid Molecular Weight on Physicochemical and Rheological Properties of Ice Cream

open access: yesFood Science &Nutrition, Volume 14, Issue 10, October 2026.
We prepared ice cream formulations, including a control with a commercial stabilizer–emulsifier blend at 0.3% and four treatments with 0.3% hyaluronic acid (HA) at different molecular weights (320, 980, 1550, and 2550 kDa), and compared them. Increasing HA molecular weight was associated with increased hardness, improved creaming stability, enhanced ...
Rutvi Joshi   +2 more
wiley   +1 more source

MEK inhibition achieves robust and durable responses in Erdheim–Chester disease

open access: yesHemaSphere, Volume 10, Issue 10, October 2026.
Abstract Erdheim–Chester disease (ECD) is a rare histiocytic neoplasm characterized by heterogeneous clinical manifestations and limited evidence to guide targeted therapy. While MEK inhibitors (MEKi) are increasingly used, data on their real‐world efficacy, durability, and safety remain incomplete.
Francesco Pegoraro   +34 more
wiley   +1 more source

Appropriate ICD Therapies in Primary Prevention: A Propensity‐Matched Comparison of Contemporary and Historic Heart Failure Cohorts

open access: yesJournal of Arrhythmia, Volume 42, Issue 5, October 2026.
No significant difference in appropriate ICD therapies between treatment eras. Time to first ICD therapy was similar after propensity‐score matching. The result was robust to a sensitivity analysis using an expanded propensity model. Cumulative incidence, accounting for competing risk of death, was also higher.
Inês Ferreira Neves   +11 more
wiley   +1 more source

Applying a Pareto‐Based Efficiency Frontier to Inform Value‐Based Pricing for Gaucher Disease Therapies in Brazil

open access: yesPharmacoepidemiology and Drug Safety, Volume 35, Issue 10, October 2026.
ABSTRACT Purpose Gaucher disease (GD) requires lifelong high‐cost treatment within the Brazilian Unified Health System (SUS). In Brazil, treatment eligibility and monitoring are defined by Clinical Protocol and Therapeutic Guidelines (PCDT), while pharmaceutical prices are regulated by the Drug Market Regulation Chamber (CMED).
Marcus Carvalho Borin   +4 more
wiley   +1 more source

PGM1 deficiency is linked to sarcomeric and mitochondrial dysfunction in patient-derived iPSC-cardiomyocytes. [PDF]

open access: yesJ Transl Med
Radenkovic S   +17 more
europepmc   +1 more source

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