Results 71 to 80 of about 12,584 (234)

Relationship between endometriosis and uterine cervical elasticity assessed using ultrasound strain elastography [PDF]

Ultrasonography
Purpose Internal cervical os (ICO) stiffness is related to menstrual pain, a key symptom of endometriosis. The study evaluated whether women with endometriosis have a stiffer ICO than unaffected women. Methods A retrospective cross-sectional analysis was
Anjeza Xholli, Filippo Molinari, Umberto Scovazzi, Ambrogio Pietro Londero, Isabella Perugi, Chiara Kratochwila, Francesca Cremonini, Angelo Cagnacci   +7 more
doaj   +1 more source

Not Missing the Notch: Detection Challenges of Juxtamembrane NOTCH1 Variant Detection in T‐Cell Acute Lymphoblastic Leukemia

Journal of Clinical Laboratory Analysis, EarlyView.
ABSTRACT Background Activating mutations in NOTCH1 are frequent in T‐cell acute lymphoblastic leukemia (T‐ALL) and, in the absence of alterations in RAS or PTEN, are associated with favorable prognosis. Besides classical heterodimerization and PEST domain mutations, juxtamembrane internal tandem duplications (JME‐ITDs) represent a third class of ...
Francisco Beas, Stephan Hutter, Ferran Balbastre‐Úbeda, Sandra Novoa‐Jáuregui, Maria Gabarrós‐Subirà, Eulalia Genescà, Petri Pölönen, Torsten Haferlach, Andrés Jerez   +8 more
wiley   +1 more source

Redefining CHI3L1: Therapeutic Opportunities at the Crossroads of Immune Suppression and Disease Progression

Medicinal Research Reviews, EarlyView.
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu, Saurabh Upadhyay, Moustafa T. Gabr   +2 more
wiley   +1 more source

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

Portal Hypertension &Cirrhosis, EarlyView.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao, Sheng Cheng, Qiaoling Pan, Jiong Yu, Hongcui Cao   +4 more
wiley   +1 more source

Climate requirements for cultivated Liberica coffee (Coffea liberica) and consequences for its use and development as a crop species

PLANTS, PEOPLE, PLANET, EarlyView.
The global coffee industry, supporting 25 million smallholder farmers, is vulnerable to climate change. Diversifying the coffee species portfolio beyond Arabica and robusta is a promising intervention. Liberica coffee could provide adaptive capacity, although its climate parameters for cultivation are poorly known.
Isobel M. J. Wild, Aaron P. Davis, Kenny Wee Ting Lee, Justin Moat   +3 more
wiley   +1 more source

ICOS regulates ILC2s in asthma

Oncotarget, 2015
Asthma is a chronic inflammation of the airways leading to airway hyperreactivity and bronchoconstriction in response to allergens as well as unspecific stimuli such as cold air [1]. Classically, the key player cells in the pathogenesis of asthma are known to be T helper cells subsets including Th2, Th9 and Th17 as well as iNK T cells and dendritic ...
Hadi, Maazi, Omid, Akbari
openaire   +2 more sources

Tracing Three Decades of Low Earth Orbit Satellite Communication Development: A Bibliometric and Main Path Analysis of Network Architectures, Protocol Evolution, and Emerging Intelligent Services

International Journal of Satellite Communications and Networking, EarlyView.
ABSTRACT Low Earth Orbit (LEO) satellite communication systems have evolved into a critical component of global broadband networks, enabling wide‐area connectivity, IoT services, and intelligent multilayer satellite–terrestrial integration. Despite rapid advancements in constellation deployment, routing mechanisms, resource management, and LEO–5G/6G ...
Wei‐Hao Su, Ya‐Chen Chuang, Long‐Sheng Chen   +2 more
wiley   +1 more source

Intracalvariosseous injection: an approach for central nervous system drug delivery through skull bone marrow with a preclinical research in strokeResearch in context

EBioMedicine
Summary: Background: Central nervous system (CNS) accessibility constitutes a major hurdle for drug development to treat neurological diseases. Existing drug delivery methods rely on breaking the blood-brain barrier (BBB) for drugs to penetrate the CNS.
Wenqian Liu, Mo Yang, Nanxing Wang, Xiangrong Liu, Chaoyu Wang, Kaibin Shi, Fu-Dong Shi, Yuesong Pan, Mingjun Zhang, Zhiwei Sun, Yongjun Wang, Yilong Wang   +11 more
doaj   +1 more source

Bitcoin vis a vis NEO: Upaya Tiongkok menuju Penyeimbang Kekuatan Ekonomi Amerika Serikat dalam Kacamata Hegemoni dan Soft Balancing

Jurnal Ilmiah Hubungan Internasional, 2019
Abstrak Bitcoin merupakan salah satu cryptocurrency yang terkenal sejak 2013 diseluruh dunia dimana konsepnya adalah P2P atau terdesentralisasi antar server user dalam sebuah jaringan.
Ika Riswanti Putranti, Pungki Retnowati
doaj   +1 more source

Ontogeny of foraging behaviour in an opportunistic gull inhabiting urban marine ecosystems

Wildlife Biology, EarlyView.
Urbanization affects ecosystems by reducing biodiversity and displacing species from native habitats. While some suffer, others, like urban wildlife, adapt through innovative feeding and behaviours that improve their fitness in human‐altered settings. Despite research on wildlife in urban areas, the development of foraging behaviour in urban species is
Joan Navarro, Víctor Martín-Vélez, Joan Giménez, José Antonio Garcia, Pablo Cermeño, Jordi Figuerola, Raül Aymí, Tomás Montalvo   +7 more
wiley   +1 more source