Results 71 to 80 of about 3,139 (175)
Non-viral Smad7 gene delivery and attenuation of postoperative peritoneal adhesion in an experimental model [PDF]
Background: Postoperative intra-abdominal adhesion is associated with high morbidity and mortality. Smad7, a protein that occupies a strategic position in fibrogenesis, inhibits the transforming growth factor (TGF) β/Smad signalling pathway.
Chan, LYY +5 more
core +1 more source
The impact of peritoneal dialysis on oxypurinol and urate elimination in people with gout
Abstract Gout affects 15%–30% of individuals with advanced kidney disease. Allopurinol which is rapidly and extensively metabolised to an active metabolite, oxypurinol, is the most commonly prescribed urate‐lowering therapy. Oxypurinol is almost entirely eliminated by the kidneys (>95%) and has an elimination half‐life of 18–30 h in those with normal ...
Luke C. Wilson +7 more
wiley +1 more source
Icodextrin reduces adhesion formation following gynecological surgery in rabbits [PDF]
Background: Adhesion is a common complication of gynecology surgery so different barrier agents and solutions have been used during these operations to separate and protect tissues from adhesion after surgery.
Behnaz Khani1 +3 more
doaj
Background This article is a duplicated publication from the Japanese version of “2019 JSDT Guidelines for Peritoneal Dialysis” with permission from the Japanese Society for Dialysis Therapy (JSDT).
Munekazu Ryuzaki +43 more
doaj +1 more source
Abstract Background Peritoneal dialysis (PD) and conventional in‐center hemodialysis (HD) are treatment options for patients with end‐stage kidney disease (ESKD). However, their impact on all‐cause mortality is unclear. Methods We conducted a multicenter, open‐label, randomized, non‐inferiority trial to determine the effect of dialysis modality on ...
Li Fan +26 more
wiley +1 more source
Symptomatic pleural effusion secondary to pleuroperitoneal communication in patients undergoing peritoneal dialysis (PD) occurs in approximately 2% of patients undergoing continuous ambulatory PD.
Macaulay Amechi Chukwukadibia Onuigbo, MD, MSc, FWACP, FASN, MBA +4 more
doaj +1 more source
Syndecan-4 knockout leads to reduced extracellular transglutaminase-2 and protects against tubulointerstitial fibrosis [PDF]
Transglutaminase type 2 (TG2) is an extracellular matrix crosslinking enzyme with a pivotal role in kidney fibrosis. The interaction of TG2 with the heparan sulfate proteoglycan syndecan-4 (Sdc4) regulates the cell surface trafficking, localization, and ...
Burhan, I +6 more
core +1 more source
Abstract Introduction Peritoneal dialysis (PD) is a life maintaining treatment in patients with end‐stage renal disease. Its chronic application leads to peritoneal mesothelial layer denudation and fibrotic transformation along with vascular activation of inflammatory pathways. The impact of different PD fluids (PDF) on mesothelial and endothelial cell
Rajesh M. Jagirdar +8 more
wiley +1 more source
Dialysis in the acute setting [PDF]
Acute kidney injury (AKI) is frequently encountered in the hospital setting. It may be present on admission or may develop during the hospital stay. Early and consistent recognition of AKI has been a challenge.
Malhotra, Kunal
core
A generalized linear model for cardiovascular complications prediction in PD patients [PDF]
[Abstract] This study was conducted using machine learning models to identify patient non-invasive information for cardiovascular complications prediction in peritoneal dialysis patients. Nowadays is well known that cardiovascular diseases are the key to
Alonso Valente, Rafael +3 more
core +1 more source

