Results 151 to 160 of about 471,112 (353)
THE PAIR EDUCATION AND INNOVATION – KNOWLEDGE SOCIETY’S ICON [PDF]
This paper uses the frame of the SWOT Analysis to introduce the EPIC Model, which is based on four elements, among which two of them we suppose are representative for the knowledge society: education and innovation.
Cristian Silviu BANACU +2 more
core
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
FEBS Open Bio, EarlyView.Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
A new discovery. The icon of «St. Sergius, Nikon and Savva»
, 2022 О.В. Петрова
openalex +2 more sources
P3 Experience with an automated breast segmentation tool for a large multi-centre organisation
Breast, 2020 Y. Hu, M. Byrne, B. Archibald-Heeren
doaj +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
The sinaitic icon of the Heavenly Ladder and Saint Anthony archbishop
, 2017 Charalampos MACHAIRAS
openalex +2 more sources