Results 91 to 100 of about 208,085 (307)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

IKON DAN INDEKS DALAM CERPEN SHUUZANZU KARYA AKUTAGAWA RYUUNOSUKE 『秋山図』という芥川龍之介の短編小説のアイコンとインデックス [PDF]

open access: yes, 2015
Tyas, RizkyFebriani. 2015. “IkondanIndeksdalamCerpenShuuzanzuKaryaAkutagawaRyuunosuke”. Thesis.Department of Japanese Studies Faculty of Humanities Diponegoro University. The First Advisor Drs. Hermintoyo, M.Pd.
Rizky, Tyas
core  

A Virtual Conversational Agent for Teens with Autism: Experimental Results and Design Lessons

open access: yes, 2020
We present the design of an online social skills development interface for teenagers with autism spectrum disorder (ASD). The interface is intended to enable private conversation practice anywhere, anytime using a web-browser.
Ali M. R.   +11 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Can auditory icons induce food intake mimicry? [PDF]

open access: yes, 2015
This research hypothesized that auditory icons that represent eating can be used to induce mimicry in food intake behavior.Numerous studies show that, when two people are eating together, they mimic each other’s eating behavior.To test this hypothesis ...
Baharin, Hanif   +2 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

The Cult of Old Believers’ Domestic Icons and the Beginning of Old Belief in Russia in the 17th-18th Centuries

open access: yesReligions, 2019
The aim of this paper is to present the cult of icons in the Old Believer communities from the perspective of private devotion. For the Old Believers, from the beginning of the movement, in the middle of the 17th century, icons were at the center of ...
Aleksandra Sulikowska-Bełczowska
doaj   +1 more source

Enhanced Management of Personal Astronomical Data with FITSManager

open access: yes, 2011
Although the roles of data centers and computing centers are becoming more and more important, and on-line research is becoming the mainstream for astronomy, individual research based on locally hosted data is still very common.
Ajit Kembhavi   +13 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

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