Results 71 to 80 of about 208,085 (307)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Some observations on the oldest icons from Marko’s Monastery (II): Time of creation [PDF]

open access: yesZograf
The text proposes a dating for the oldest icons from Marko’s Monastery near Skopje, taking into account the sources on the monastery’s ktetors. In particular, it highlights the fact that the proportions of the existing altar barrier, created during the ...
Marković Miodrag
doaj   +1 more source

An iconic programming language for sensor-based robots [PDF]

open access: yes
In this paper we describe an iconic programming language called Onika for sensor-based robotic systems. Onika is both modular and reconfigurable and can be used with any system architecture and real-time operating system.
Gertz, Matthew   +2 more
core   +1 more source

The hardness of the iconic must: Can Peirce’s existential graphs assist modal epistemology? [PDF]

open access: yes, 2009
The current of development in 20th century logic bypassed Peirce’s existential graphs, but recently much good work has been done by formal logicians excavating the graphs from Peirce’s manuscripts, regularizing them and demonstrating the soundness and ...
Legg, Catherine
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Peisaj urban – edificii semnal [PDF]

open access: yesUrbanism. Arhitectura. Constructii, 2010
The paper defines, based on the definitions of icons, indexes and symbols, a conceptual framework used to look at specific case studies in order to derive the meaning of signal-constructions.
Andreea Grigorovschi   +1 more
doaj  

iPod... icon

open access: yes, 2008
The iPod became, for a moment at least, iconic amongst those hand-held electronic devices with buttons and screens, noises and "connectivity" that proliferated at the beginning of the twenty-first century. This essay explores how the iPod, in becoming an unobtrusive memory machine as absent as an internal organ on the body of its user, provides a ...
openaire   +2 more sources

Iconics: Icon Evolution in Digitality

open access: yestripleC: Communication, Capitalism & Critique. Open Access Journal for a Global Sustainable Information Society, 2010
Image manipulation, archiving, and sharing are all critical technological aspects of Western culture and postmodern civilization. Consequently, creation, identification, dissemination, and proliferation of powerful images across media channels today indicate a burgeoning area of information technology.While words alone are capable of conveying adequate
openaire   +3 more sources

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

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