Results 111 to 120 of about 206,500 (292)

Enhanced Management of Personal Astronomical Data with FITSManager

open access: yes, 2011
Although the roles of data centers and computing centers are becoming more and more important, and on-line research is becoming the mainstream for astronomy, individual research based on locally hosted data is still very common.
Ajit Kembhavi   +13 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Comparison of Effective and Non-Effective Icons in the Searching Module Concerning Familiarity and Meaningfulness in Azarakhsh, Simorgh and Nika Digital Libraries [PDF]

open access: yesکتابداری و اطلاع‌رسانی, 2016
Purpose: The present study aimed to compare effective and non-effective icons in the searching module with regard to familiarity and meaningfulness in Azarakhsh, Simorgh and Nika digital libraries.
Mahdieh Mirzabegi   +2 more
doaj  

Icones Aroidearum,

open access: yes
Heinrich Wilhelm Schott (1794-1865), botanist and gardener. Born at Brno (today: Czech Republic) January 7th 1794, died at Schönbrunn (today within the city of Vienna, Austria) March 5th 1865, son of the gardener Heinrich Schott (1759-1819).- Schott attended botanical lectures of Nikolaus Joseph von Jacquin (1727-1817) and Joseph Franz von Jacquin ...
openaire   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Jesus’ Descent into Hell

open access: yesSt Andrews Encyclopaedia of Theology
The Apostles’ Creed affirms that, between his death and resurrection, Jesus Christ descendit ad inferna, ‘descended to the realm of the dead’ or, more traditionally, ‘descended into hell’.
Preston McDaniel Hill   +1 more
doaj  

The Reception of Aristotle in “On Icons” by St. John Damascene

open access: yesForum Theologicum Sardicense
This text will explore Aristotle’s influence on the defense of the veneration of holy images in St. John of Damascus’s Three Apologetic Treatises against Those Decrying the Holy Images.
Alena Kerezova
doaj   +1 more source

April Fools’ Day, A Celebration of All Things Creative

open access: yes, 2015
April Fools\u27 Day is unique among our holidays because it is the only one for which ingenuity is required. Other festivals are celebrated with expectations of prepackaged icons.
Gimbel, Steven
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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