Results 111 to 120 of about 23,238 (188)
Management of advanced mycosis fungoides and Sézary Syndrome: International Recommendations for systemic treatments and allogeneic hematopoietic cell transplantation from the European Hematology Association, the EORTC Cutaneous Lymphoma Tumours Group, the International Society for Cutaneous Lymphoma, and the Lymphoma Working Party of the EBMT
HemaSphere, Volume 10, Issue 11, November 2026.Abstract
Advanced mycosis fungoides (MF) and Sézary syndrome (SS) are the most aggressive forms of cutaneous T‐cell lymphoma and remain associated with a poor prognosis and heterogeneous therapeutic approaches. Recent advances, including targeted therapies and improved transplant strategies, have substantially expanded treatment options, highlighting ...Francesco Onida, Pietro Quaglino, Julia Scarisbrick, Anna Sureda, Emmilia Hodak, Evangelia Papadavid, Silvia Alberti‐Violetti, Martine Bagot, Lorenzo Cerroni, Amrita Goyal‐O'Leary, Rudolf Stadler, Rein Willemze, Jasmine Zain, Marco Ardigò, Emilio Berti, Adèle de Masson, Rafael F. Duarte, Francine Foss, Eva González‐Barca, Joan Guitart, Pablo Ortiz‐Romero, Alessandro Pileri, Pierluigi Porcu, Henry M. Prince, Sima Rozati, Serena Rupoli, Maarten H. Vermeer, Sean Whittaker, Nicola Pimpinelli, Pier Luigi Zinzani +29 morewiley +1 more sourceImpact of venetoclax‐based therapies on CLL‐associated autoimmune cytopenias: A retrospective study conducted by ERIC
HemaSphere, Volume 10, Issue 11, November 2026.Abstract
The impact of venetoclax‐based therapies on autoimmune cytopenias (AIC) in patients with chronic lymphocytic leukemia (CLL) is largely unknown. This study aimed to evaluate preexisting and treatment‐emergent AIC in patients with CLL treated with venetoclax, focusing on the differential impact of venetoclax monotherapy versus venetoclax‐based ...Candida Vitale, Thomas Chatzikonstantinou, Christina Papangelou, Francesca Perutelli, Maria Chiara Montalbano, Giulia Bondielli, Elia Boccellato, Salem Alshemmari, Francesco Angotzi, Miguel Arguello‐Tomas, Tomas Arpas, Sandra Bašić‐Kinda, Sotiria Besikli‐Dimou, Łukasz Bołkun, Tomasz Buczek, Aleksandra Butrym, Katherine Chapis, Sofia Chatzileontiadou, Rosa Collado, Raul Cordoba Mascuñano, Lorenzo De Paoli, Marina Deodato, Maria Dimou, David Donaldson, Joanna Drozd‐Sokołowska, Salem Elias, Andrea Ferrario, Alberto Fresa, Anna Maria Frustaci, Rocío García‐Serra, Ajay Gogia, Isabel González‐Gascón‐y‐Marín, Vasko Graklanov, Maria Hryniewiecka, Zhu Huayuan, Elzbieta Iskierka‐Jażdżewska, Paula Jablonowska‐Babij, Ozren Jaksic, Elzbieta Kalicińska, Maria Kislova, Maya Koren‐Michowitz, Epameinondas Koumpis, Zuzana Kubová, Jorge Labrador, Pietro Lauzzana, Shai Levi, Francesca Martini, Mariia Mikhaleva, Eva Minga, Riccardo Moia, Elżbieta Morawiec‐Szymonik, Marta Morawska, Femke V. M. Mulder, Roberta Murru, Jacopo Olivieri, Ewa Paszkiewicz‐Kozik, Lata Rani, Josep Maria Roncero, Wojciech Salamon, Alessandro Sanna, Lydia Scarfò, Tereza Shokralla, Martin Šimkovič, Matevž Škerget, Emil Spasov, Antigoni Tranidou, Jagoda Tryc‐Szponder, Marzia Varettoni, Andrea Visentin, George Vrachiolias, David Waddell, Ewa Wasik‐Szczepanek, Kamil Wdowiak, Mateusz Wilk, Kamil Wiśniewski, Magdalena Witkowska, Mohamed Yassin, Seyma Yıldız, Klaudia Zielonka, Nil Albiol, Jennifer R. Brown, Benedetto Bruno, Mark Catherwood, Anastasia Chatzidimitriou, Michael Doubek, Gianluca Gaidano, Alessandro Gozzetti, Ritu Gupta, Eleftheria Hatzimichael, Yair Herishanu, Krzysztof Jamroziak, Ioannis Kotsianidis, Luca Laurenti, Eugene Nikitin, Maria Papaioannou, Tomáš Papajik, Martin Špaček, Niki Stavroyianni, Josephine M. I. Vos, Tomasz Wróbel, Münci Yağcı, Arnon P. Kater, Matthew Davids, Petra Langerbeins, Kostas Stamatopoulos, Paolo Ghia, Marta Coscia +106 morewiley +1 more sourceGITR and GITR-L RNA Expression Levels Correlate with Better Survival and Response to Immunotherapy. [PDF]
Mol Cancer TherMoussa P, Kurzrock R, Nishizaki D, Miyashita H, Lee S, Nikanjam M, Jensen TJ, Conroy JM, DePietro P, Sicklick JK, Kato S. +10 moreeuropepmc +1 more sourceImmune Markers and Risk of Pancreatic Cancer in the European EPIC Cohort
International Journal of Cancer, Volume 159, Issue 9, Page 2146-2157, 1 November 2026.The immune system has been implicated as a major driver in pancreatic cancer etiology. Previous cohort studies have found associations between pancreatic cancer and single immune system‐derived markers, but omics‐based evidence remains scarce. In this prospective case–control study, the authors investigated 92 proteins involved in immune reactions and ...Verena A. Katzke, Yue Chen, Srimanti Dutta, Federico Canzian, Julie Louise Munk Andersen, Agnetha Linn Rostgaard‐Hansen, Léa Bouteille, Vinciane Rebours, Thérèse Truong, Matthias B. Schulze, Benedetta Bendinelli, Valeria Pala, Vittorio Simeon, Rosario Tumino, Carlotta Sacerdote, Roel Vermeulen, P. Martijn Kolijn, Sjoerd G. Elias, Marta Crous‐Bou, Maria‐José Sánchez, Ana Jimenez‐Zabala, José María Huerta, Marcela Guevara, Nick Wareham, Marie Breeur, Mattias Johansson, James Yarmolinsky, Daniele Campa, Rudolf Kaaks +28 morewiley +1 more sourceMulti‐Omics Insights Into Circulating T‐Cell Metabolic Reprogramming and Treg Dysfunction in Moyamoya Disease
MedComm, Volume 7, Issue 11, November 2026.The comprehensive study design is illustrated. A multi‐omics approach was used to characterize T‐cell metabolic alterations in MMD. By integrating mass cytometry (CyTOF), single‐cell RNA sequencing (scRNA‐seq), bulk RNA‐seq, metabolomics, and flow cytometry, we aimed to elucidate metabolic reprogramming in circulating T cells and Treg dysfunction in ...Zhiyao Zheng, Qiheng He, Xinyu Ma, Bojian Zhang, Junsheng Li, Chenglong Liu, Siqi Mou, Wei Sun, Xiangjun Shi, Wenjing Wang, Dong Zhang, Peicong Ge, Jizong Zhao +12 morewiley +1 more sourceICOS-Targeted Peptide Imaging Informs Therapeutic Response of STING Agonist in Lung Adenocarcinoma. [PDF]
J Nucl MedDuan S, Tan B, Mao Y, Zhang Y, Lou H, Wei X, Qu C, Li C, Jing C, Xia Y, Duan Z, Cheng Z, Wu C, Xiao Z. +13 moreeuropepmc +1 more sourceRegulatory T Cells in Health and Disease
MedComm, Volume 7, Issue 11, November 2026.Regulatory T cells (Tregs) arise through distinct developmental pathways and adapt to specialized tissue niches to maintain immune tolerance, barrier integrity, and metabolic homeostasis. In disease, Tregs undergo context‐dependent changes, ranging from functional insufficiency and lineage instability in autoimmune, inflammatory, cardiovascular, and ...Mingyi Li, Si Zhang, Tangchun Wu, Tingting Tang, Xiang Cheng +4 morewiley +1 more sourceA Pan‐Hepatic T‐Cell Atlas Identifies Disease‐Specific Immune Dysfunction and Therapeutic Targets for Immunotherapy
MedComm, Volume 7, Issue 11, November 2026.A Pan‐HEpatic single‐cell Atlas of T cells (Pheat) was constructed covering chronic hepatitis, cirrhosis, hepatocellular carcinoma (HCC), and healthy controls. CD8+ exhausted T cells (Tex) and CD4+ regulatory T cells (Treg) were delineated profound through decoding molecular and cellular variance, immune checkpoint networks, pathway analysis, and drug ...Si‐Yuan Chen, You‐Yuan Wang, Shuang‐Nan Zhou, Ming‐Ju Zhou, Xia Li, Wei‐Zhe Li, Meng‐Meng Zhu, Yu‐Xuan Yang, Ying Sun, Peiyao Fan, Jing Li, Xing Fan, Ruonan Xu, Yan‐Mei Jiao, Jin‐Wen Song, Cheng Zhen, Ming Shi, Chao Zhang, Fu‐Sheng Wang +18 morewiley +1 more source
