Results 131 to 140 of about 29,154 (297)

European Obspack compilation of atmospheric nitrous oxide data from ICOS stations for the period 1996-2025; obspack_n2o_466_GV_ICOSFT2025.1_20250120

open access: yes
This data package contains high accuracy N2O dry air mole fractions from 26 ICOS European observatories at in total 73 observation levels, collected by the ICOS Atmosphere Thematic Centre (ATC) and provided by the station contributors.
et al   +2 more
core   +1 more source

Cardiotoxicity of BRAF/MEK inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Rapidly accelerated fibrosarcoma type B/B‐Raf proto‐oncogene, serine/threonine kinase (BRAF) and mitogen‐activated protein kinase (MEK) inhibitors have transformed outcomes in cancer therapy, particularly in melanoma. However, cardiovascular toxicities are increasingly recognized in real‐world clinical practice.
Katharina Seuthe   +4 more
wiley   +1 more source

ICOS Ligation Recruits the p50{alpha} PI3K Regulatory Subunit to the Immunological Synapse.: ICOS-p50α interactions

open access: yes, 2008
International audienceICOS ligation in concert with TCR stimulation results in strong PI3K activation in T lymphocytes. The ICOS cytoplasmic tail contains an YMFM motif that binds the p85alpha subunit of class IA PI3K, similar to the YMNM motif of CD28 ...
Fos, Camille   +9 more
core   +1 more source

Microbiome–Driven Carcinogenesis and Circulating Microbial Signals in Genitourinary Cancers

open access: yesCancer Science, EarlyView.
Experimental BBN models link gut microbial metabolism and diet‐microbiome interactions to urothelial carcinogenesis, while circulating extracellular vesicle‐associated bacterial DNA signals may reflect tumor immune contexture and immune checkpoint inhibitor outcomes in urothelial and renal cell carcinoma.
Atsunari Kawashima   +12 more
wiley   +1 more source

Functional comparison of ICOS/ICOS-L and CD28/CD80-CD86 in the cooperation of T cells and dendritic cells

open access: yes, 2003
Inhalt und Publikation Einleitung Material und Methoden Ergebnisse Diskussion Referenzen ZusammenfassungDendritische Zellen (DC) initiieren und unterhalten die T-Zell-vermittelte Immunantwort.
Witsch, Esther Julia
core   +1 more source

Behaviour Support in Dentistry Core Outcomes (BeSiDe‐CO): A Core Outcome Set Development Study

open access: yesCommunity Dentistry and Oral Epidemiology, EarlyView.
ABSTRACT Objectives To develop a Core Outcome Set suitable for adults and children for use in studies of Dental Behaviour Support (DBS) techniques, including non‐pharmacological DBS, sedation and General Anaesthesia research. Methods Two systematic reviews generated a preliminary list of candidate outcomes that were shared with Key Stakeholders (KSG ...
Caoimhin Mac Giolla Phadraig   +22 more
wiley   +1 more source

ICOS-expressing CAR-T cells mediate durable eradication of triple-negative breast cancer and metastasis

open access: yesJournal for ImmunoTherapy of Cancer
Triple-negative breast cancer (TNBC) remains one of the most aggressive and therapeutically challenging breast cancer subtypes. In their recent study, Cao et al introduced a B7H3-specific chimeric antigen receptor (CAR)-T cell with constitutive inducible
Padmanee Sharma   +2 more
doaj   +1 more source

Adherence to Treatment in Allergic Rhinitis During the Pollen Season in Europe: A MASK‐air Study

open access: yesClinical &Experimental Allergy, Volume 55, Issue 3, Page 226-238, March 2025.
In a study assessing mobile health data, (i) adherence to rhinitis medication was highest for oral antihistamines and lowest for azelastine‐fluticasone, (ii) in weeks of partial adherence, azelastine‐fluticasone was associated with lower levels of reported rhinitis symptoms than other medication classes.
Bernardo Sousa‐Pinto   +121 more
wiley   +1 more source

Initial Coin Offering (ICOs) : determinants of successful Initial Coin Offering (ICOs) [PDF]

open access: yes, 2019
O objetivo desta dissertação é identificar as determinantes que influenciam o sucesso de uma Initial Coin Offering (ICO). Especificamente, este trabalho investiga diferentes abordagens usadas para lançar com sucesso uma Initial Coin Offering (ICO) e ...
Cruz, Diogo Filipe Barros
core  

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