Results 141 to 150 of about 29,154 (297)

Understanding and addressing resistance to IMiDs immunomodulatory compounds in multiple myeloma

The FEBS Journal, EarlyView.
IMiDs are pivotal in the treatment of multiple myeloma. Mechanisms of resistance comprise cell intrinsic and extrinsic pathways, involving tumour microenvironment, immune cell dysfunction, CRBN‐dependent and independent genetic drivers and epigenetic changes.
Maria‐Cynthia Fuentes‐Lacouture, Devi Nandana, Karthik Ramasamy, Anjan Thakurta   +3 more
wiley   +1 more source

ICOS IN BELGIUM: WALLONIA [PDF]

, 2014
Présentation ICOS ...
De Ligne, Anne
core  

Senescent Human Liver Endothelial Cells Mediate CD4+ T Cell Recruitment via ICOSL

Immunology, EarlyView.
In this study, we detect senescent endothelial cells within chronically diseased human liver tissues. Next, we develop a novel protocol for the induction of paracrine senescence in primary human liver endothelial cells and explore their functionality.
Daniel A. Patten, Amy Lumley, Alex L. Wilkinson, Ayla O’Keeffe, Kelvin Yin, Niranjan Shirgaonkar, Ran Gao, Ramanuj DasGupta, Matthew Hoare, Shishir Shetty   +9 more
wiley   +1 more source

Gold nanoparticle catalyst for the aerobic oxidation of alcohols under ambient conditions

, 2009
1
박재욱
core  

Family quality‐of‐life burden in chronic spontaneous urticaria: A multicentre study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Poor control of chronic spontaneous urticaria (CSU) significantly worsens family members' quality of life, especially in emotional, physical, and social domains. Higher disease severity was linked to increased caregiving burden and household expenditures, highlighting the need for family‐centred CSU care and support across diverse global populations ...
Beatrice Martinez Zugaib Abdalla, Roberta Fachini Jardim Criado, Kanokvalai Kulthanan, Emek Kocatürk, Ivan Cherrez‐Ojeda, Ana Maria Giménez‐Arnau, Marcus Maurer, Luis Felipe Ensina, Jonathan A. Bernstein, Michihiro Hide, Sergio Duarte Dortas Junior, Solange Oliveira Rodrigues Valle, Gabriela Dias, Paraskevi Xepapadak, Priyanshi Dangi, Indrashis Podder, Vesna Trajkova, Natasa Teovska Mitrevska, Iman Hamed Nasr, Bushra Al Hinai, Joanna Bartosińska, Dorota Krasowska, Paulina Szczepanik‐Kułak, Hilal Gungor, Deniz Ozceker, Kübra Çiçek, Esen Özkaya, Yasemin Erdem, Mücahit Ergün, Mustafa Tosun, Rabia Oztas Kara, Jie Li, Anastasia Allenova, Paulo Ricardo Criado   +33 more
wiley   +1 more source

ICOS: An Intelligent MetaOS for the Continuum

Proceedings of the 2nd International Workshop on MetaOS for the Cloud-Edge-IoT Continuum
This paper presents ICOS, a meta-operating system designed for the cloud continuum. The paper provides insight into the ICOS architecture, focusing on the Intelligence Layer and highlighting the benefits and functionalities it provides to administrators and users of the edge-to-cloud continuum.
Garcia Almiñana, Jordi, Masip, Xavi, Giannopoulos, Anastasios, Trakadas, Panagiotis, Cajas, Sebastián A., Samanta, Jaydeep, Suárez Cetrulo, Andrés León, Simon Carbajo, Ricardo, Michalke, Marc, Jukan, Admela, Jaworski, Artur, Kotliński, Marcin, Giammatteo, Gabriele, D'Andria, Francesco   +13 more
openaire   +1 more source

CD4+ T Cells Predict Relapse in Pemphigus Vulgaris Treated With Rituximab: A Retrospective Study

Oral Diseases, EarlyView.
ABSTRACT Objective This study evaluated the CD4+ T‐cell role in mediating post‐Rituximab Pemphigus vulgaris (PV) relapse, comparing CD4+ count and CD4+/CD20+ ratio between patients who achieved remission and those who relapsed. Methods The clinical course of 27 PV patients treated with Rituximab was evaluated after a 32‐month median follow‐up. CD4+ and
Simone Liguori, Noemi Coppola, Elvira Ruoppo, Federica Canfora, Gabriele Mignogna, Ilaria Mormile, Antonia Fiore, Giuseppe Castaldo, Michele Davide Mignogna, Stefania Leuci   +9 more
wiley   +1 more source

‘Taking inaction on carbon sinks to court’1 in Ireland? Comparative analysis of Finnish and German cases

Review of European, Comparative &International Environmental Law, EarlyView.
Abstract The carbon sink capacity of ecosystems has long been neglected, leading to their degradation and the release of stored carbon, thereby exacerbating climate change. As parties increasingly resort to courts to resolve controversies over the sufficiency of measures to combat climate change, carbon sinks are emerging as a focal point.
Alessandra Accogli, Amelia Burnette
wiley   +1 more source

Non-invasive imaging with ICOS-targeting monoclonal antibody for preclinical diagnosis of rheumatoid arthritis in a humanized mouse model

Journal of Translational Medicine
Background Activated T cells play a pivotal role in rheumatoid arthritis (RA) pathogenesis, and imaging of activated T cells may provide a non-invasive tool for RA detection.
Shao Duan, Chao Li, Feng Yan, Yifei Xia, Shuaiming Shao, Weiyu Chen, Zunyu Xiao, Gongping Xu   +7 more
doaj   +1 more source

The Construction of Compliance with the European Union Deforestation Regulation in Global Coffee Value Chains

Regulation &Governance, EarlyView.
ABSTRACT The European Union's Deforestation Regulation (EUDR) obliges the importers and users of seven agricultural commodities to achieve supply chain traceability and prevent deforestation‐linked products from entering the EU market. This paper investigates how companies and producing countries in the coffee sector prepared for EUDR compliance by ...
Janina Grabs
wiley   +1 more source