Results 141 to 150 of about 117,111 (323)

Functional CRISPR‐Cas9 knockout screening of the genetic determinants of human fibroblast migration propensity

Biotechnology Progress, EarlyView.
Abstract Directional cell migration plays a central role in a wide range of physiological and pathological conditions, such as embryonic development or tumor metastasis. Steps involved in cell migration include cell polarization, formation of membrane protrusions at the cell front side and adhesion disassembly at the rear side, and a general ...
Antonio Mazzei, Sebastian Martewicz, Ramin Amiri, Meihua Cui, Nicola Elvassore, Camilla Luni   +5 more
wiley   +1 more source

Cosmic Strings Stabilized by Fermion Fluctuations

, 2011
We provide a thorough exposition of recent results on the quantum stabilization of cosmic strings. Stabilization occurs through the coupling to a heavy fermion doublet in a reduced version of the standard model. The study combines the vacuum polarization
Birman M. Sh., HERBERT WEIGEL, Krein M. G., Krein M. G., MARKUS QUANDT, NOAH GRAHAM, Stojkovic D.   +6 more
core   +1 more source

Cutting Edge: ICOS-Deficient Regulatory T Cells Display Normal Induction of Il10 but Readily Downregulate Expression of Foxp3

Journal of Immunology, 2019
The ICOS pathway has been implicated in the development and functions of regulatory T (Treg) cells, including those producing IL-10. Treg cell–derived IL-10 is indispensable for the establishment and maintenance of intestinal immune homeostasis.
Ashley E. Landuyt, B. Klocke, Tyler B. Colvin, T. Schoeb, Craig L. Maynard   +4 more
semanticscholar   +1 more source

Cardiovascular toxicity induced by TKIs in patients with chronic myeloid leukaemia: Are women and men different?

ESC Heart Failure, Volume 12, Issue 2, Page 1447-1454, April 2025.
This study analyzes 148 patients (66 women and 82 men) with chronic myeloid leukemia treated with tyrosine kinase inhibitors, focusing on cardiovascular adverse events. The risk assessment, performed using the HFA/ICOS score, reveals sex‐specific differences: venous thrombosis is more common in women, while arterial thrombosis predominates in men.
Cristina Madaudo, Daniela Di Lisi, Antonio Cannatà, Federica Manfrè, Celeste Vullo, Marco Santoro, Ciro Botta, Salvatrice Mancuso, Sergio Siragusa, Alfredo Ruggero Galassi, Giuseppina Novo   +10 more
wiley   +1 more source

Report of the SNOMS Project 2006 to 2012, SNOMS SWIRE NOCS Ocean Monitoring System. Part 1: Narrative description

, 2013
The ocean plays a major role in controlling the concentration of carbon dioxide (CO2) in the atmosphere. Increasing concentrations of CO2 in the atmosphere are a threat to the stability of the earth’s climate.
Campbell, J.M., Donahoe, J., Hartman, M.C., Hartman, S.E., Hydes, D.J., Jiang, Z-P., Kelly-Gerreyn, B.A., Pagnani, M.   +7 more
core  

An Imaging Fabry-Perot System for the Robert Stobie Spectrograph on the Southern African Large Telescope

, 2008
We present the design of the Fabry-Perot system of the Robert Stobie Spectrograph on the 10-meter class Southern African Large Telescope and its characterization as measured in the laboratory.
Atherton, Atherton, Bland-Hawthorn, Charles L. Joseph, Chris Pietraszewski, Ciddor, Fowles, Gelderman, Lemarquis, Mahapatra, Naseem Rangwala, Netterfield, Ramsay, Ryder, T. B. Williams, Vaughan   +15 more
core   +1 more source

Examine Ico

, 2018
Shanghai Shellpay Internet Technology Co., Ltd.
openaire   +1 more source

Post‐surgery level of circulating DNA in stage III colon cancer patients: Impact on the reliability of minimal residual disease detection

International Journal of Cancer, EarlyView.
What's New? Circulating nuclear DNA (cir‐nDNA)‐based assessment of minimal residual disease (MRD) offers powerful post‐surgery prognostic insight for stage III colon cancer (CC). Sparse knowledge of post‐surgical variations and origins in cir‐nDNA, however, has limited its clinical application.
Andrei Kudriavtsev, Saidi Daoud, Catalina Isabel Cofre Muñoz, Alexia Mirandola, Ekaterina Pisareva, Javier Gonzalo Ruiz, Marco Macagno, Nadia Saoudi Gonzalez, Evelyne Crapez, Marc Ychou, Ramon Salazar Soler, Elisabetta Fenocchio, Paula X. Fernandez Calotti, Thibault Mazard, Cristina Santos Vivas, Elena Elez, Federica Di Nicolantonio, Alain R. Thierry   +17 more
wiley   +1 more source

TCF1 and LEF1 Control Treg Competitive Survival and Tfr Development to Prevent Autoimmune Diseases. [PDF]

, 2019
CD4+ Foxp3+ T regulatory (Treg) cells are key players in preventing lethal autoimmunity. Tregs undertake differentiation processes and acquire diverse functional properties.
Cho, Sunglim, Dong, Yi, Feng, Gen-Sheng, Fu, Wenxian, Jepsen, Kristen, Liang, Yan, Lu, Li-Fan, Wan, Shuo, Wang, Ke, Xu, Wanqing, Xue, Hai-Hui, Yang, Bi-Huei, Yuan, Xiaomei   +12 more
core   +1 more source

Kryptonite for Cryptocurrencies? What Are the Effects of Regulatory Controls on Bitcoin Returns and Volatility?

International Journal of Finance &Economics, EarlyView.
ABSTRACT This paper examines the impact of regulatory controls on Bitcoin's excess returns and volatility. The paper innovates by proxying changes in the regulatory environment using global Google search volume intensity data. The generated regulatory indices accurately identify episodes of regulatory tightening within cryptocurrency markets.
Robert Mullings
wiley   +1 more source