Results 231 to 240 of about 180,532 (304)

A leaf phenomics approach for estimating belowground traits in North American licorice

open access: yesAmerican Journal of Botany, EarlyView.
Abstract Premise Selective breeding over thousands of years has prioritized aboveground yield, with little regard for changes belowground. Roots underpin plant growth and resilience, but our knowledge of these critical structures lags behind that of aboveground structures.
Zachary N. Harris   +5 more
wiley   +1 more source

Cancer therapy‐induced ototoxicity: Current challenges and emerging management strategies

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This review comprehensively examines the key risk factors for cancer therapy‐induced ototoxicity, including cumulative drug dose, genetic susceptibility, and combined treatment regimens. It highlights current challenges in ototoxicity monitoring, such as insufficient timeliness and limited clinical adoption, and advocates for standardized auditory ...
Yuqi Huang   +4 more
wiley   +1 more source

Single-Pulse Response LA-ICP-MS Imaging with Quadrupole Instrumentation: Theoretical Considerations and Practical Assessment. [PDF]

open access: yesAnal Chem
Willner J   +6 more
europepmc   +1 more source

Cerebrospinal Fluid from Restless Legs Syndrome Patients Reduces Iron Uptake in Blood–Brain Barrier Endothelial Cells by Disrupting the Regulation of Transferrin Receptors

open access: yesAnnals of Neurology, EarlyView.
Model figure of BBBECs TfR1 regulation in control and RLS: Graphical representation of TfR1 regulation in ECs by IRPs and representing it can be dysregulated by miR‐124‐3p in ECs of RLS. FPN1, ferroportin; BBBEC, blood‐brain barrier endothelial cells; IRP, iron regulatory proytein1/2; TfR1, Transferrin receptor; IRE, Iron responsive elements; Tf ...
Kondaiah Palsa   +6 more
wiley   +1 more source

ICP-MS for Multiplexed Protein Determination in Extracellular Vesicles from APP/PS1 Mice Blood Serum-Application to a Zn Supplementation Pilot Study. [PDF]

open access: yesAnal Chem
Martínez-García J   +6 more
europepmc   +1 more source

A Doxorubicin‐Loaded Liposomes Baghdadite System for Localized Osteosarcoma Therapy and Bone Regeneration

open access: yesAdvanced NanoBiomed Research, EarlyView.
This study presents a multifunctional Baghdadite ceramic implant integrating doxorubicin‐loaded liposomes via ion‐assisted plasma polymer coating for localized osteosarcoma therapy. The platform enables drug retention, sustained release, tumor cell inhibition, osteoconductivity, and antibacterial activity, offering a mechanically robust strategy for ...
Sally Kortam   +8 more
wiley   +1 more source

Toward Multi(radio)metalated DNA: Enzymatic Polymerization of Metal‐Chelate‐Modified Deoxyribonucleoside Triphosphates

open access: yesAngewandte Chemie, EarlyView.
This work presents the first enzymatic polymerization of defined metal‐chelator‐modified nucleotides that leverage polymerase fidelity for uniform (radio)metal loading with successful incorporation of five different metals: Ga, In, Tb, Lu, and Y.
Antonio A. W. L. Wong   +2 more
wiley   +1 more source

Multi‐Objective Catalyst Discovery in High‐Entropy Alloy Composition Space: The Role of Noble Metals on the Pareto Front for Oxygen Reduction Reaction

open access: yesAngewandte Chemie, EarlyView.
Pareto optimal compositions of alloy catalyst for oxygen reduction reaction are uncovered through multi‐objective Bayesian optimization of activity, stability, and material cost in an eight‐element high‐entropy alloy composition space. The substantial Pareto front obtained is compared to experimental literature and analyzed to elucidate the roles and ...
Mads K. Plenge   +4 more
wiley   +1 more source

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