Results 131 to 140 of about 48,964 (396)
Advanced Science, EarlyView.The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang +15 more
wiley +1 more source
Subicular Astrocytes Govern Seizure‐Impaired Fear Memory
Advanced Science, EarlyView.Astrocytes in dorsal subiculum act as a critical modulator of seizure‐associated cognitive dysfunction, operating through a Ca2+‐dependent adenosine‐linked astrocyte‐neuron signaling pathway that disrupts neuronal circuit homeostasis. This research highlights the potential of astrocyte‐targeted interventions as a therapeutic strategy, moving beyond the
Yuying Shao +15 more
wiley +1 more source
Revista KranionEl ictus en la edad pediátrica es una emergencia neurológica infradiagnosticada. Solo se diagnostican en fase aguda el 48% de estos ictus. Con frecuencia el diagnóstico es tardío. Como consecuencia, los supervivientes van a presentar importantes secuelas motoras, cognitivas o del lenguaje.
Paloma Menéndez-Valladares +9 more
openaire +2 more sources
Historia natural de la oclusión aguda de gran arteria de la circulación cerebral anterior : serie clínica de 120 pacientes [PDF]
, 2012 : Para estudiar la historia natural del ictus isquémico por oclusión de gran vaso de la circulación anterior se seleccionó una muestra prospectiva de pacientes con ictus agudo que no recibieron terapias de reperfusión en los que se confirmó una oclusión ...
Dávalos, Antoni +4 more
core
Advanced Science, EarlyView.Identifying disease‐causing genes in neurocognitive disorders remains challenging due to variants of uncertain significance. CLinNET employs dual‐branch neural networks integrating Reactome pathways and Gene Ontology terms to provide pathway‐level interpretability of genomic alterations.
Ivan Bakhshayeshi +5 more
wiley +1 more source
Hospital arrival times and delay before acute stroke patients receive neurological care. Analysis of a national multi-centre registry: EPICES registry (II) [PDF]
, 2012 Trabajo publicado por Castillo J, Vivancos-Mora J, en nombre de los investigadores del registro EPICESIntroducción. Los tiempos en la llegada al hospital o el retraso hospitalario en la atención especializada a los pacientes con ictus siguen siendo la
Castillo Sánchez, José +1 more
core +1 more source
Organic Electrochemical Transistors in Tissue‐Interfaced Bioelectronics
Advanced Science, Volume 13, Issue 6, 30 January 2026.This article reviews the design, fabrication, and biological application of organic electrochemical transistors (OECTs), emphasizing their potential in tissue‐interfaced bioelectronics. It covers the fundamental principles of OECTs, strategies for enhancing tissue interfacing, and the development of skin‐mounted and implantable systems.
Ruixiang Bai, Zeyu Zhao, Feng Yan
wiley +1 more source
Impacto de la implementación de un centro terciario de ictus en la atención médica de pacientes con ictus isquémico agudo por disección de arterias cervicales [PDF]
, 2013 Evaluamos el impacto que la implementación del centro terciario de ictus (CTI) en nuestro hospital ha tenido sobre el manejo de los pacientes con ictus isquémico por disección de arterias cervicales (DAC) comparando características diagnósticas ...
Almendrote Muñoz, Míriam +4 more
core
Stretchable Curvature Sensors for Motion Capture with Bending‐Stretching Coupling Deformation
Advanced Science, EarlyView.Stretchable curvature sensors based on a wavy symmetric stacked‐layer structure (WSSLS) enable decoupled bending‐stretching detection with high linearity, repeatability, and durability. Integrated into smart gloves, the sensors achieved precise motion capture and human‐robot interaction, with slip‐simulation tests demonstrating a remarkable 93.6 ...
Tairan Wang +9 more
wiley +1 more source