Results 131 to 140 of about 20,996 (348)

Discordance Between Systemic Lupus Erythematosus Disease Activity Index Domain Weights and Their Association With Organ Damage Accrual

open access: yesArthritis Care &Research, EarlyView.
Objective Studies of damage accrual in patients with systemic lupus erythematosus (SLE) show associations with disease activity measured by the SLE Disease Activity Index 2000 (SLEDAI‐2K), but these associations are imperfect. SLEDAI scores are powerfully influenced by weightings (1–8) assigned to each domain.
Kevin Zhang   +8 more
wiley   +1 more source

Ictus isquémico: avances y proyecciones

open access: yes, 2014
OBJECTIVE: To present the main advances and projections related with ischemic stroke management.DEVELOPMENT: This article look at some recent aspects considered in specialized journals about: 1) Definition of stroke types, 2) Genetic risk factors of ...
Rodríguez García, Pedro Luis
core  

Registro prospectivo de ictus intrahospitalarios [PDF]

open access: yes, 2012
Antecedentes: Los ictus intrahospitalarios (IIH) son frecuentes, suponen entre el 4.4 y el 15% del total de ictus. Tienen mayor gravedad y peor pronóstico.
Vera Lechuga, Rocío
core  

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

open access: yesAdvanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Fibronectin1‐Expressing Subicular Circuits Selectively Govern the Retrieval of Novel Object Recognition

open access: yesAdvanced Science, EarlyView.
Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei   +15 more
wiley   +1 more source

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

open access: yesAdvanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng   +8 more
wiley   +1 more source

ICTUS

open access: yes, 2018
Según la OMS, se registran al año 6,7 millones de muertes que son causadas por accidentes cerebrovasculares; por lo que instituciones como Valle del Lili implementan estrategias para disminuir la mortalidad por esta causa. El doctor Pablo Amaya, con ayuda de neurólogos, neurocirujanos, neuro-radiologos, terapeutas endovasculares y especialistas en ...
openaire   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

open access: yesAdvanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak   +9 more
wiley   +1 more source

Ictus Hemorrágico y calidad de vida [PDF]

open access: yes, 2015
Los accidentes cerebrovasculares (ACV), también denominados Ictus, se producen por una alteración en los vasos sanguíneos que aportan sangre al cerebro, bien por la rotura de estos vasos o por la oclusión que sufren como consecuencia de un coágulo.
Ríos Cuesta, Valeria de los
core  

Stroke health care plan (ICTUS II. 2010)

open access: yes, 2011
Introduction: The Spanish Stroke Group published the “Plan for stroke healthcare delivery” in 2006 with the aim that all stroke patients could receive the same degree of specialized healthcare according to the stage of their disease, independently of ...
E. Martínez-Vila   +18 more
core   +1 more source

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