Results 91 to 100 of about 895,090 (346)

Mortality in intensive care: The impact of bacteremia and the utility of systemic inflammatory response syndrome [PDF]

, 2016
Background: The purpose of this study was to determine the impact of bacteremia on intensive care unit (ICU) mortality and to develop a bacteremia prediction tool using systemic inflammatory response syndrome (SIRS) criteria. Methods: Patients
Booth, Malcolm G., Brooks, Daniel, Fulton, Rachael, Smith, Andrew, Young, Douglas   +4 more
core   +1 more source

Effect of Flexible Family Visitation on Delirium Among Patients in the Intensive Care Unit: The ICU Visits Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2019
Importance The effects of intensive care unit (ICU) visiting hours remain uncertain. Objective To determine whether a flexible family visitation policy in the ICU reduces the incidence of delirium.
R. Rosa, M. Falavigna, D. D. da Silva, D. Sganzerla, M. M. Santos, Renata Kochhann, Rafaela Moraes de Moura, C. Eugênio, Tarissa da Silva Ribeiro Haack, M. G. Barbosa, C. Robinson, Daniel Schneider, D. M. de Oliveira, R. Jeffman, A. Cavalcanti, F. Machado, L. Azevedo, J. Salluh, J. Pellegrini, R. Moraes, R. Foernges, A. Torelly, Liz Ayres, P. Duarte, W. J. Lovato, P. Sampaio, L. C. de Oliveira Júnior, J. L. R. Paranhos, A. Dantas, Pollyanna Iracema Peixoto Gouveia Gomes de Brito, Eliane Aparecida Peixoto Paulo, M. Gallindo, Janaina Pilau, Helen Martins Valentim, José Mário Meira Teles, V. Nobre, D. Birriel, Livia Corrêa e Castro, Andréia Martins Specht, G. Medeiros, T. Tonietto, E. C. Mesquita, N. B. da Silva, J. Korte, L. Hammes, A. Giannini, F. Bozza, C. Teixeira   +47 more
semanticscholar   +1 more source

Behavior Decoding Delineates Seizure Microfeatures and Associated Sudden Death Risks in Mouse Models of Epilepsy

Annals of Neurology, EarlyView.
Objective Behavior and motor manifestations are distinctive yet often overlooked features of epileptic seizures. Seizures can result in transient disruptions in motor control, often organized into specific behavioral sequences that can inform seizure types, onset zones, and outcomes.
Yuyan Shen, Jaden Thomas, Xianhui Chen, Jaden Zelidon, Mariam Najeeb, Abigayle Hahn, Ping Zhang, Aaron Sathyanesan, Bin Gu   +8 more
wiley   +1 more source

Detecting Awareness in the Intensive Care Unit Using Functional Near‐Infrared Spectroscopy

Annals of Neurology, EarlyView.
Objective Signs of awareness after acute severe brain injury are critical for informing goals‐of‐care decisions, ranging from the continuation of aggressive life‐sustaining therapy to comfort‐focused end‐of‐life measures. However, awareness may go undetected in some critically ill patients when assessed using bedside behavioral neurological examination.
Karnig Kazazian, Jack de Jeu, Androu Abdalmalak, Sergio L. Novi, Matthew Kolisnyk, Garima Gupta, Laura E. Gonzalez‐Lara, Teneille E. Gofton, Loretta Norton, Derek B. Debicki, Adrian M. Owen   +10 more
wiley   +1 more source

Sepsis caused by bloodstream infection in patients in the intensive care unit: the impact of inactive empiric antimicrobial therapy on outcome [PDF]

, 2018
Background: Sepsis is one of the leading causes of death in the UK. Aims: The aims of this study were to identify the rate of inactive antimicrobial therapy (AMT) in the ICU and whether inactive AMT had an effect on in hospital mortality, ICU ...
Booth, M.G., Brooks, Daniel, Polubothu, Padmaja, Smith, A., Young, D.   +4 more
core   +1 more source

Impact of Interleukin‐1 Blockade on the Development of Macrophage Activation Syndrome in Still Disease: Incidence and Diagnostic Validity of the EULAR/ACR/PRINTO 2016 MAS Classification Criteria

Arthritis &Rheumatology, EarlyView.
Objective To evaluate the applicability of the 2016 European Alliance of Associations for Rheumatology (EULAR)/American College of Rheumatology (ACR)/Paediatric Rheumatology International Trials Organisation (PRINTO) macrophage activation syndrome (MAS) classification criteria in patients with Still disease and systemic juvenile idiopathic arthritis ...
Remco G. A. Erkens, Greta Rogani, Laura Huber, Anouk Verwoerd, Dieneke Schonenberg‐Meinema, J. Merlijn van den Berg, Wineke Armbrust, G. Elizabeth Legger, Sylvia Kamphuis, Ellen J. H. Schatorjé, Esther P. A. H. Hoppenreijs, Joost F. Swart, Marc H. A. Jansen, Jorg van Loosdregt, Sebastiaan J. Vastert   +14 more
wiley   +1 more source

Using Shock Index as a Predictor of ICU Readmission: A Quality Iimprovement Project [PDF]

, 2015
Background: Adverse events will occur in one-third of patients discharged from the intensivecare unit (ICU) and evidence shows that ICU readmissions increase a patient’s length of stay,mortality, hospital costs, and nosocomial infections, as well as ...
Sykes, Melissa
core   +1 more source

Effect of an ICU Diary on Posttraumatic Stress Disorder Symptoms Among Patients Receiving Mechanical Ventilation: A Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2019
Importance Keeping a diary for patients while they are in the intensive care unit (ICU) might reduce their posttraumatic stress disorder (PTSD) symptoms.
M. Garrouste-Orgeas, C. Flahault, I. Vinatier, J. Rigaud, N. Thieulot-Rolin, E. Mercier, Antoine Rouget, Hubert Grand, O. Lesieur, F. Tamion, R. Hamidfar, A. Renault, E. Parmentier-Decrucq, Y. Monseau, L. Argaud, C. Bretonnière, A. Lautrette, J. Badie, É. Boulet, B. Floccard, X. Forceville, Eric Kipnis, L. Soufir, S. Valade, N. Bigé, Alain Gaffinel, O. Hamzaoui, G. Simon, M. Thirion, L. Bouadma, A. Large, J. Mira, Nora Amdjar-Badidi, M. Jourdain, Paul-Henri Jost, V. Maxime, F. Santoli, S. Ruckly, C. Vioulac, Marie Annick Leborgne, Lucie Bellalou, L. Fasse, B. Misset, S. Bailly, J. Timsit   +44 more
semanticscholar   +1 more source

A systematic scoping review of metrics utilized to measure antibiotic consumption in hospital settings

British Journal of Clinical Pharmacology, EarlyView.
Abstract Antimicrobial stewardship (AMS) programs were introduced to promote the judicious use of antimicrobials and to combat antimicrobial resistance. Quantifying antibiotic consumption is an important part of AMS initiatives to achieve these objectives.
Marjan Kandimahforoujaki, Kiplin A. Patanwala, Jan‐Willem C. Alffenaar, Asad E. Patanwala   +3 more
wiley   +1 more source

Pharmacokinetics of teicoplanin in paediatric patients—A systematic review of current literature

British Journal of Clinical Pharmacology, EarlyView.
Background and Objective Teicoplanin is commonly used in children to treat gram‐positive infections and is sometimes used off‐label prophylactically in surgical or paediatric oncology settings. The pharmacokinetics (PK) of teicoplanin in children exhibit considerable variability, such as in critically ill children or those with renal impairment.
Noa E. Wijnen, Daan J. Touw, Kim Klein, Gertjan J. L. Kaspers, Paola Mian   +4 more
wiley   +1 more source