Results 61 to 70 of about 895,090 (346)

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

open access: yesAdvanced Healthcare Materials, EarlyView.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao   +2 more
wiley   +1 more source

Antidepressant Use and Depressive Symptoms in Intensive Care Unit Survivors [PDF]

open access: yes, 2017
Nearly 30% of intensive care unit (ICU) survivors have depressive symptoms 2-12 months after hospital discharge. We examined the prevalence of depressive symptoms and risk factors for depressive symptoms in 204 patients at their initial evaluation in the
Boustani, Malaz   +8 more
core   +1 more source

Antibacterial and Osteogenic Applications of Ti‐Cu Alloys: A Review of Current Research and Future Directions

open access: yesAdvanced Materials Interfaces, EarlyView.
Given the growing interest in antibiotic‐free implant strategies and the need for biocompatible solutions to combat peri‐implantitis and implant failure, this review gives a timely and comprehensive overview of Ti‐Cu alloys as next‐generation biomaterials.
Brandon Fields   +8 more
wiley   +1 more source

Bioelectronic Sensors for Neuromuscular Perception in Human‐Machine Interfaces

open access: yesAdvanced Robotics Research, EarlyView.
This review summarizes recent advances in bioelectronic sensors for neuromuscular perception in human‐machine interfaces. By integrating biopotential, electrical impedance, and electrochemical sensing strategies with flexible electrode interfaces, these bioelectronic sensing systems enable intuitive, real‐time detection of muscle and nerve activity ...
Junwei Li   +5 more
wiley   +1 more source

Extreme Dysbiosis of the Microbiome in Critical Illness. [PDF]

open access: yes, 2016
Critical illness is hypothesized to associate with loss of "health-promoting" commensal microbes and overgrowth of pathogenic bacteria (dysbiosis). This dysbiosis is believed to increase susceptibility to nosocomial infections, sepsis, and organ failure.
Christine Baird   +12 more
core   +2 more sources

RIPK1 Drives JAK1‐STAT3 Signaling to Promote CXCL1‐Mediated Neutrophil Recruitment in Sepsis‐Induced Lung Injury

open access: yesAdvanced Science, EarlyView.
This article examines the central role of RIPK1 in the pathogenesis of sepsis‐induced lung injury. It elucidates how RIPK1 initiates an inflammatory cascade by activating JAK1‐STAT3 signaling, leading to CXCL1‐mediated neutrophil infiltration. Importantly, it demonstrates that pharmacological inhibition of RIPK1 effectively attenuates inflammation and ...
Hao Sun   +15 more
wiley   +1 more source

Association between acute gastrointestinal injury and biomarkers of intestinal barrier function in critically ill patients

open access: yesBMC Gastroenterology, 2017
Background To assess the associations of biomarkers of intestinal barrier function and other clinical variables with acute gastrointestinal injury (AGI) grade, and of these clinical variables with mortality in critically ill patients.
Hongxiang Li   +4 more
doaj   +1 more source

Refractory Status Epilepticus and Therapeutic Uncertainties: a Comprehensive Review on Targeting Neuroinflammation and Rationale for Developing a Platform Trial

open access: yesAdvanced Science, EarlyView.
Refractory status epilepticus (RSE) is a life‐threatening neurological emergency with high rates of death and long‐term disability, but treatments for it are often based on limited evidence. RSE is now understood to involve neuroinflammation, which has led to the exploration of anti‐inflammatory and immunomodulatory agents like Tocilizumab. Traditional
Shanika Samarasekera   +12 more
wiley   +1 more source

Practical approach to diastolic dysfunction in light of the new guidelines and clinical applications in the operating room and in the intensive care [PDF]

open access: yes, 2018
There is growing evidence both in the perioperative period and in the field of intensive care (ICU) on the association between left ventricular diastolic dysfunction (LVDD) and worse outcomes in patients.
Morelli, A.   +3 more
core   +1 more source

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