Results 91 to 100 of about 12,634,313 (292)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

AMČR - dokument C-3D-202000503

open access: yes, 2015
Stav: 3Označení: Id 2157910Popis: Úštěp. Kultura neolit. Lokalita Bylany (ČR)
https://api.aiscr.cz/id/ORG-000094   +1 more
core   +1 more source

Examining the Relationship between Psychosocial Work Factors and Musculoskeletal Discomfort among Computer Users in Malaysia [PDF]

open access: yesIranian Journal of Public Health, 2011
Background: With computers rapidly carving a niche in virtually every nook and crevice of today's fast-paced society, mus­culoskeletal disorders are becoming more prevalent among computer users, which comprise a wide spectrum of the Ma­laysian population,
SA Zakerian, ID Subramaniam
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

¿Poseen capacidades de innovación las empresas farmacéuticas de América Latina? La evidencia de Argentina, Brasil, Cuba y México

open access: yesEconomía Teoría y Práctica, 2009
El sector farmacéutico ha sido considerado por algunos países como estratégico porque, en la medida en que es capaz de hacer frente a los problemas de salud de la población, contribuye al bienestar social y al crecimiento económico.
Alenka Guzmán, María Victoria Guzmán
doaj  

Analysis of pressure variation of fluid in bounded circular reservoirs under the “No Flow” outer boundary condition

open access: yesJournal of Applied Sciences and Environmental Management, 2017
Predicting the pressure at the wellbore in bounded circular reservoir has been the hub in the study of Reservoir Engineering. Predicting the pressures outside the reservoir was not an easy task.
ID Erhunmwun, JA Akpobi
doaj   +1 more source

IDE-IDE PEMBAHARUAN FAZLUR RAHMAN

open access: yesALQALAM, 1997
Ide-Ide Pembaharuan Fazlur ...
openaire   +2 more sources

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

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