Results 81 to 90 of about 10,890,628 (275)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Augmented Cardiopulmonary Baroreflex Sensitivity in Intradialytic Hypertension. [PDF]

open access: yes, 2018
IntroductionEnd-stage renal disease (ESRD) patients with a paradoxical increase in blood pressure (BP) during hemodialysis (HD), termed intradialytic hypertension (ID-HTN), are at significantly increased risk for mortality and adverse cardiovascular ...
DaCosta, Dana R   +5 more
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Examining the Relationship between Psychosocial Work Factors and Musculoskeletal Discomfort among Computer Users in Malaysia [PDF]

open access: yesIranian Journal of Public Health, 2011
"nBackground: With computers rapidly carving a niche in virtually every nook and crevice of today's fast-paced society, mus­culoskeletal disorders are becoming more prevalent among computer users, which comprise a wide spectrum of the ...
SA Zakerian, ID Subramaniam
doaj   +2 more sources

Investigation of Moral Hazard Deportments in Community-Based Health Insurance in Guto Gida District, Western Ethiopia: A Qualitative Study

open access: yesClinicoEconomics and Outcomes Research, 2020
Isubalew Daba Ayana Department of Economics, Wollega University, Nekemte, EthiopiaCorrespondence: Isubalew Daba AyanaDepartment of Economics, Wollega University, Nekemte, EthiopiaEmail isubalewmsc@gmail.comIntroduction: Ethiopia introduced CBHI in 2011 ...
Ayana ID
doaj  

Unlawfully Present Aliens, Driver’s Licenses, and Other State-Issued ID: Select Legal Issues [PDF]

open access: yes, 2014
[Excerpt] This report provides an overview of key legal issues raised by state laws regarding the denial or issuance of driver’s licenses and other forms of ID to unlawfully present aliens.
Garcia, Michael John, Manuel, Kate M
core   +2 more sources

Defects in the (d+id)-wave superconducting state in heavily doped graphene

open access: yes, 2014
A chiral time-reversal symmetry breaking (d+id)-wave superconducting state is likely to emerge in graphene doped close to the Van Hove singularity.
Black-Schaffer, Annica M.   +1 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Improvements to the Producer Price Index measure: The Final-Demand-Intermediate-Demand System [PDF]

open access: yes, 2014
[Excerpt] The release of January 2014 Producer Price Index (PPI) data marks the transition from the Stage of Processing (SOP) aggregation system to the Final Demand–Intermediate Demand (FD–ID) aggregation system.
Borgie, Lana   +3 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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