Results 81 to 90 of about 6,962,642 (291)

Comparative Psychoanalytic Study Of Poe’s “the Oval Portrait” And Hawthorne’s “the Birthmark”

The Journal of Studies in Language, Culture and Society
The present study discusses Psychological concepts such as id, Eros, obsession, narcissism, and aggression as they are represented in Hawthorne’s “The Birthmark” (1843) and Poe’s “The Oval Portrait” (1842).
Hejazi Bayan
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Distribution of ampullary pores on three catshark species (Apristurus spp.) suggest a vertical-ambush predatory behaviour

Aquatic Biology, 2014
Apristurus is a genus of typically small sharks that inhabit deep waters around the globe. Relatively little is known about the feeding behaviour of these species. Here, the electrosensory biology of 3 species, A. aphyodes, A. melanoasper and A. microps,
DM Moore, ID McCarthy
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Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

ISRĀĪLĪYĀT: PERKEMBANGAN DAN DAMPAKNYA DALAM TAFSIR AL-QUR`AN

Islamuna: Jurnal Studi Islam, 2015
Al-Qur`an mengungkapkan kisah-kisah umat terdahulu, baik sebagai ibrah, penukilan hukum dan penjelasan ketauhidan serta pengungkapan kisah yang sebenarnya.
Ahmad Sa`id Samsuri
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Langage et muséographie : Réflexions sur le pouvoir des mots dans les espaces muséaux

Limes
Dans le contexte postcolonial marocain, caractérisé par une pluralité linguistique (amazigh, arabe, français) et des enjeux de représentation culturelle, l’article analyse le rôle des choix linguistiques muséographiques à l’Agadir Musée d’Art dans la ...
Omar ID TNAINE
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IDE-IDE PEMBAHARUAN FAZLUR RAHMAN

ALQALAM, 1997
Ide-Ide Pembaharuan Fazlur ...
openaire   +2 more sources

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

¿Poseen capacidades de innovación las empresas farmacéuticas de América Latina? La evidencia de Argentina, Brasil, Cuba y México

Economía Teoría y Práctica, 2009
El sector farmacéutico ha sido considerado por algunos países como estratégico porque, en la medida en que es capaz de hacer frente a los problemas de salud de la población, contribuye al bienestar social y al crecimiento económico.
Alenka Guzmán, María Victoria Guzmán
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