Results 61 to 70 of about 12,634,313 (292)
, 2016 This report presents the activities and achievements of INESC-ID in 2016, highlighting its mission to develop cutting-edge technologies through excellence in research.
Aurélia Constantino
core
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
, 2009 This annual report from INESC-ID presents an overview of the research and development activities conducted by the institution in 2009. The main contribution of this work lies in its documentation of the institution's progress towards achieving its ...
Aurélia Constantino
core
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
, 2015 This annual report provides an overview of INESC-ID's research activities and achievements in 2015, focusing on advanced research and development in Electronics, Communications, Information Technologies, and Energy.
Aurélia Constantino
core
, 2023 The authors are grateful to SAIA (ID 45748 ) and Enamine for research ...
Сливка, Михайло Васильович +3 more
core
IDGenerator: unique identifier generator for epidemiologic or clinical studies
BMC Medical Research Methodology, 2016 Background Creating study identifiers and assigning them to study participants is an important feature in epidemiologic studies, ensuring the consistency and privacy of the study data.
Matthias Olden +3 more
doaj +1 more source
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
, 2019 This report presents the activities and achievements of INESC-ID in 2019, highlighting its contributions to advanced research in engineering, information technology, and energy. The institution's mission is to produce value for society through innovation,
Aurélia Constantino
core
AMČR - samostatný nález C-202109132-N00556
Stav: 4Evideční číslo: 556Poznámka: římsko-provinciální kování opasku, fragment (druhá polovina k fragmentu s PAS-ID C-202109132 ...
https://api.aiscr.cz/id/OS-007414
core +1 more source