Results 51 to 60 of about 2,900,589 (294)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Scientific Reports, 2023 The NeoVAD is a proposed paediatric axial-flow Left Ventricular Assist Device (LVAD), small enough to be implanted in infants. The design of the impeller and diffuser blades is important for hydrodynamic performance and haemocompatibility of the pump ...
Lee Nissim +5 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The Idea of Kosmopolis : Two Kinds of Cosmopolitanism
, 2008 The idea of ...
Lettevall, Rebecka
core +5 more sources
Vitae, 2014 Antecedentes: Las microalgas son fuente de compuestos fisiológicamente activos que pueden ser usados como ingredientes funcionales. De las microalgas del género Arthrospira (Spirulina) perteneciente a las algas verde-azules y cuyas especies más ...
Alexia TORRES +3 more
doaj
Frontiers in Robotics and AISocial robots are increasingly being utilized to address mental health challenges in older adults, such as depression, anxiety, and loneliness. However, ethical concerns surrounding their use are insufficiently explored in empirical research.
Lillian Hung +4 more
doaj +1 more source
An idea model for distributed Idea Management [PDF]
2010 IEEE International Technology Management Conference (ICE), 2010 Processes of Open Innovation and innovation in Living-Labs applying the co-creation paradigm do involve many participating innovators across different organisations and stakeholder groups. This is especially true when dealing with disruptive or radical innovations instead of incremental ones.
Duin, Heiko +3 more
openaire +2 more sources
Ten Research-Based Steps for Effective Group Work
, 2017 Active learning approaches often involve students working in groups. The advantage of this pedagogical choice is that students can apply concepts, solve problems, and, in general, engage cognitively with course content with the support of peers ...
Hodges, Linda
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source