Results 51 to 60 of about 8,022,606 (207)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Ethical considerations in the use of social robots for supporting mental health and wellbeing in older adults in long-term care

Frontiers in Robotics and AI
Social robots are increasingly being utilized to address mental health challenges in older adults, such as depression, anxiety, and loneliness. However, ethical concerns surrounding their use are insufficiently explored in empirical research.
Lillian Hung, Lillian Hung, Yong Zhao, Hadil Alfares, Parsa Shafiekhani   +4 more
doaj   +1 more source

Racial Differences in Breastfeeding Initiation Among Participants in a Midwestern Public Health District

Health Equity, 2018
Purpose: Although variations in breastfeeding initiation are well documented, the contributing role of maternal race remains poorly understood, especially among the multiracial?two or more races?population.
Maria Pineros-Leano, Maria Pineros-Leano, Karen M. Tabb, Karen M. Tabb, Shannon D. Simonovich, Shannon D. Simonovich, Yang Wang, Yang Wang, Brandon Meline, Brandon Meline, Hsiang Huang, Hsiang Huang   +11 more
doaj   +1 more source

Reduction in mobility and COVID-19 transmission

Nature Communications, 2021
Social distancing policies aiming to reduce COVID-19 transmission have been reflected in reductions in human mobility. Here, the authors show that reduced mobility is correlated with decreased transmission, but that this relationship weakened over time ...
Pierre Nouvellet, Sangeeta Bhatia, Anne Cori, Kylie E. C. Ainslie, Marc Baguelin, Samir Bhatt, Adhiratha Boonyasiri, Nicholas F. Brazeau, Lorenzo Cattarino, Laura V. Cooper, Helen Coupland, Zulma M. Cucunuba, Gina Cuomo-Dannenburg, Amy Dighe, Bimandra A. Djaafara, Ilaria Dorigatti, Oliver D. Eales, Sabine L. van Elsland, Fabricia F. Nascimento, Richard G. FitzJohn, Katy A. M. Gaythorpe, Lily Geidelberg, William D. Green, Arran Hamlet, Katharina Hauck, Wes Hinsley, Natsuko Imai, Benjamin Jeffrey, Edward Knock, Daniel J. Laydon, John A. Lees, Tara Mangal, Thomas A. Mellan, Gemma Nedjati-Gilani, Kris V. Parag, Margarita Pons-Salort, Manon Ragonnet-Cronin, Steven Riley, H. Juliette T. Unwin, Robert Verity, Michaela A. C. Vollmer, Erik Volz, Patrick G. T. Walker, Caroline E. Walters, Haowei Wang, Oliver J. Watson, Charles Whittaker, Lilith K. Whittles, Xiaoyue Xi, Neil M. Ferguson, Christl A. Donnelly   +50 more
doaj   +1 more source

IP Basics: Patenting Your Idea [PDF]

, 2015
This discussion addresses the relationship between patents and the market value of inventions, as well as the need to be skeptical of invention promoters and other matters of importance to first-time inventors.
Field, Thomas G., Jr.
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Efecto de la suplementación de sémola de trigo con Arthospira platensis sobre calidad, aceptabilidad y composición física y química de espaguetis

Vitae, 2014
Antecedentes: Las microalgas son fuente de compuestos fisiológicamente activos que pueden ser usados como ingredientes funcionales. De las microalgas del género Arthrospira (Spirulina) perteneciente a las algas verde-azules y cuyas especies más ...
José Alexander PARRA, Diego ROJAS, Rodolfo FENÁNDEZ-GÓMEZ, Yolmar Patricia Valero   +3 more
doaj  

Rising Up

Southern Spaces, 2008
This excerpt from the 2005 Community Ideas Station film, Rising Up, depicts challenges to segregated spaces in 1960 Richmond, Virginia.
Community Idea Stations
doaj   +1 more source

THE DEVELOPMENT OF AN IDEA [PDF]

, 1974
Whereas certain people start with a recollection or an experience and paint that experience, to some of us the act of doing it becomes the experience; so that we are not quite clear why we are engaged in a particular work.
Stikas, Marianne
core   +1 more source