Results 71 to 80 of about 4,737,123 (357)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Access to IDEA Data by People with Disabilities, For People with Disabilities
Developmental Disabilities Network JournalThe Rhonda Weiss Center for Accessible IDEA Data is a project funded by the U.S. Department of Education's Office of Special Education Programs (OSEP). The Weiss Center works with states to make IDEA data accessible to people with disabilities.
Johan Rempel, Fred Edora
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Molecular Systems Biology, 2020 Abstract Transcription factors (TFs) control the rate of mRNA production. Technological advances have made the task of measuring mRNA levels for all genes straightforward, but identifying causal relationships between TFs and their target genes remains an unsolved problem in biology.
Christopher Jackson, David Gresham
openaire +3 more sources
Virtual communication curbs creative idea generation
Nature, 2022 Melanie S. Brucks, Jonathan Levav
semanticscholar +1 more source
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2018 Introduction Current models posit a sequence of amyloid β (Aβ), tau, atrophy, and cognitive change leading to Alzheimer's disease, but ambiguities remain. We examined these sequences via serial mediations.
Evan Fletcher +6 more
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Ассистент для разработчиков в среде IntelliJ IDEA [PDF]
, 2018 В данной работе представлено расширение для IntelliJ IDEA, которое предлагает варианты решения распространённых проблем, возникающих в ходе разработки программного обеспечения.
Kita Mikhail +1 more
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