Results 91 to 100 of about 4,737,123 (357)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

თბილისის ბიზნეს რუქა

open access: yes, 2006
თბილისის ბიზნეს რუქაWissol ...
Global Idea
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

NIMBY (IDEA Design Excellence Awards)

open access: yes, 2006
WINNER of the Australian IDEA Design Awards Category: Concept - Project : Nimby IDEA, the (inside) Design Excellence Awards, is Australia's most prestigious interdisciplinary awards, celebrating design that changes the way we think, live and interact ...
Minnaert, F
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Adaptación al cambio climático en Venezuela: ¿quiénes y cómo se investiga?

open access: yesREDES: Revista Hispana para el Análisis de Redes Sociales, 2018
La construcción de una agenda de Adaptación al cambio climático es un proceso políticamente complejo, ni neutral, ni intrínsecamente benigno que crea un campo discursivo para la acción de distintas entidades sociales, con intereses y perspectivas ...
María Daniela Torres-Alruiz   +1 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

The Idea of Economics in a University [PDF]

open access: yes
Relying on John Henry Newman’s Idea of a University, this paper explores the relation between economics and other disciplines. Newman had high regard for disciplinary specialization, which he thought would teach students and scholars how to think and ...
Gabriel Martinez
core  

Idea del No [PDF]

open access: yes, 2014
Este trabajo analiza la figura del sujeto imaginario de la poesía de Idea Vilariño y trata de discernirlo no sólo en todos los enunciados que dicen "yo" en el poema, sino también en este "otro yo" que se nombra en el diario y a la vez se escande dual en ...
Monteleone, Jorge Jose
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

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