Results 101 to 110 of about 8,022,606 (207)

Poincaré and the idea of a group [PDF]

, 2012
In many different fields of mathematics and physics Poincaré found many uses for the idea of a group, but not for group theory. He used the idea in his work on automorphic functions, in number theory, in his epistemology, Lie theory (on the so-called ...
Gray, Jeremy
core  

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

A Taphonomic Study of DS-22A (Bed I, Olduvai Gorge) and Its Implications for Reconstructing Hominin-Carnivore Interactions at Early Pleistocene Anthropogenic Sites

Quaternary
The longstanding debate over early hominin subsistence strategies, particularly the hunting-versus-scavenging hypothesis, as well as discussions regarding the functionality of Oldowan sites, has been primarily centered on the archeological and ...
Blanca Jiménez-García, Gabriel Cifuentes-Alcobendas, Enrique Baquedano, Manuel Domínguez-Rodrigo   +3 more
doaj   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

From inclusion to empowerment: advancing equity through co-research with people living with dementia

Frontiers in Dementia
Too often, people living with dementia are spoken for rather than spoken with. This reflects deeply embedded assumptions/biases about people living with dementia in our society.
Lillian Hung, Joey Wong, Karen Lok Yi Wong, Emily Ong, Granville Johnson, Helen Rochford-Brennan, Jim Mann, Lester Gierach, Lynn Jackson, Mario Gregorio, Mary Beth Wighton, Mary Beth Wighton, Phyllis Fehr   +12 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

New Jewish Specialty Camps: From Idea to realIty [PDF]

, 2014
Informing Change's evaluation of the Incubator and its camps from 2009 to 2013 addressed five questions, which examined whether and how:1. The new camps had expanded available opportunities for Jewish youth to attend camp 2.
Ellen Irie, Sheila Wilcox, Tina Cheplick
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Barriers and facilitators to implementing strategies for reducing inappropriate antipsychotic use in long-term care: a scoping review

BMC Geriatrics
Background Inappropriate use of antipsychotics negatively affects the quality of life of residents in long-term care (LTC). Despite efforts to reduce inappropriate antipsychotic use, understanding of how to implement antipsychotic reduction strategies ...
Karen Lok Yi Wong, Lillian Hung, Joey Oi Yee Wong, Yong Zhao, Adebusola Adekoya, Ian Chan, Jason Wong, Annette Berndt, Jim Mann, Katrina Yuen, Arwen Fong, Mary Van, Paulina Santaella, Enhui Zhang, Sanaz Javanbakht, Krisztina Vasarhelyi   +15 more
doaj   +1 more source

A New ‘Idea of Nature’ for Chemical Education [PDF]

, 2013
This paper recommends that chemistry educators shift to a different ‘idea of nature’, an alternative ‘worldview.’ Much of contemporary science and technology deals in one way or another with dynamic coherences that display novel and important properties.
Earley, Joseph E.
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