Results 71 to 80 of about 412,613 (258)
UNIVERSITY INNOVATIVE TECHNOLOGIES
Литьë и металлургия, 2012 Methods of selection and appraisal of own technology (product, service, idea) which reflects its readiness for commercialization are offered.
V. G. Kucherov
doaj
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
The concept of internal selection and the subjection of Evolutionary Developmental Biology to the variational model of explanation [PDF]
Biotemas, 2008 The idea of internal selection, originally proposed by Lancelot Whyte, not only helps us to understand the causal status of developmental constraints, but can also show us how these organismic or internal factors, whose relevancy Evolutionary ...
Gustavo Caponi
doaj
Interação em Psicologia, 2017 This paper is a reflection on the idea according to which there is a kind of selection dedicated to cultural practices. I will argue that this proposal was based upon a metaphorical extension of natural selection to the cultural dimension.
Diego Zilio
doaj +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Selección interna: el control de la filogenia por la ontogenia en una perspectiva variacional
Theoria, 2009 La idea de selección interna, propuesta originalmente por Lancelot Whyte, no sólo sirve para entender el papel causal que los constreñimientos del desarrollo tienen en evolución; sino que además puede hacernos comprender de qué modo esos factores ...
Gustavo Caponi
doaj +1 more source
Astrocyte heterogeneity in brain metastases
Molecular Oncology, EarlyView.Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver +2 more
wiley +1 more source
Rapid Automatic Motor Encoding of Competing Reach Options
Cell Reports, 2017 Mounting neural evidence suggests that, in situations in which there are multiple potential targets for action, the brain prepares, in parallel, competing movements associated with these targets, prior to implementing one of them.
Jason P. Gallivan +4 more
doaj +1 more source
From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care
Molecular Oncology, EarlyView.Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source