Results 61 to 70 of about 413,198 (258)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Market Neutral Portfolio Selection: A Pedagogic Illustration
Spreadsheets in Education, 2013 This paper considers market neutral portfolio selection, which is an advanced investment topic. It draws on an idea in the investment literature that short selling a stock in practice is like investing in an artificially constructed security.
Clarence C. Y. Kwan
doaj
How generative AI supports human in conceptual design
Design ScienceGenerative Artificial Intelligence (Generative AI) is a collection of AI technologies that can generate new information such as texts and images. With its strong capabilities, Generative AI has been actively studied in creative design processes. However,
Liuqing Chen +5 more
doaj +1 more source
Sensor Selection method for IoT systems – focusing on embedded system requirements
MATEC Web of Conferences, 2016 Recently, various types of sensors have been developed. Using these sensors, IoT systems have become hot topics in embedded system domain. However, sensor selections for embedded systems are not well discussed up to now.
Hirayama Masayuki
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Innovation Proficiency and Barriers to Its Development by Product Managers and Their Teams
BusinessesInnovation proficiency is widely recognized as essential to organizational competitiveness; yet, how product managers and their teams develop these proficiencies across organizational contexts remains understudied.
Sara L. Beckman +5 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Subjective valuation as a domain-general process in creative thinking
Communications PsychologyIs a talented painter also a proficient writer? The ongoing discourse on whether creativity operates through domain-general or domain-specific mechanisms has led to challenges in our understanding of the creative process.
Gino Battistello +3 more
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source