Results 61 to 70 of about 6,532,743 (274)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Desilusão: Impasses Clínicos e Políticos diante dos Dilemas de nosso Tempo
Revista Subjetividades, 2018 Acontecimentos sociais e políticos, nacionais e internacionais, têm abalado nosso cotidiano. Conquistas que pareciam sedimentadas na direção da democracia e nos temas relativos aos direitos humanos, conquistas sociais e considerações éticas na vida ...
Miriam Debieux Rosa +2 more
doaj +1 more source
Creativity Studies, 2022 The study examines the creative process using the logical and methodological analysis of Plato’s concepts. It presents the modern scientific research related directly or indirectly to his philosophical views (the structural analogy method, the theory of ...
Anatoliy Stoletov
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Números y significaciones. La idealidad en la fenomenología incipiente de Husserl
Anales del Seminario de Historia de la Filosofía, 2017 La reflexión sobre los números y las significaciones es una buena muestra de cómo la fenomenología incipiente se sitúa en el terreno de la lógica pura. El artículo plantea que, para trazar una reflexión que no rasgue la personalidad filosófica de Husserl,
José Manuel Chillón
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Ideal magnetic dipole scattering
, 2017 We introduce the concept of tunable ideal magnetic dipole scattering, where a nonmagnetic nanoparticle scatters lights as a pure magnetic dipole.
Feng, Tianhua +3 more
core +1 more source
Alternative Therapies for Eye Inflammation: Patient Preferences and Patterns
International Journal of Traditional and Complementary Medicine ResearchObjective: To evaluate the prevalence and patterns of complementary and alternative medicine (CAM) use among patients with inflammatory eye disease.Methods: This cross-sectional study was conducted over three months through direct interviews with 150 ...
Bilge Yurdakul
doaj +1 more source
Profil Guru Ideal dalam Perspektif Siswa Madrasah Aliyah
Asatiza, 2020 Profil Guru yang ideal adalah sosok sesorang yang menunjukkan kemampuan dalam melaksanakan tugas nya sesuai empat kompetensi, yaitu kompetensi pedagogik, kompetensi profesional, kompetensi sosian dan kompetensi kepribadian. Tugas dan fungsi guru mengajar,
Anis Monica
doaj +1 more source