Results 81 to 90 of about 26,011 (307)

A Combined Computational and Experimental Study on Nanoparticle Transport and Partitioning in the Human Trachea and Upper Bronchial Airways

Aerosol and Air Quality Research, 2020
In the past few decades, the transport and deposition of aerosol in the human respiratory tract has been a crucial area of research, resulting in the identification of the toxicity pathways of inhaled pollutants and facilitating the design of efficient ...
Jiawei Ma, Wei-Chung Su, Yi Chen, Yidan Shang, Jingliang Dong, Jiyuan Tu, Lin Tian   +6 more
doaj   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Modeling the fluid dynamics of the heart: from blood flows in idealized left ventricles to patient-specific aortic valve simulations

, 2015
The computational fluid dynamics of the heart represents a challenging task both in terms of mathematical and numerical modeling; this is mainly due to the pulsatile nature of the blood flow, to its complex interaction with the valves, and, more in ...
TAGLIABUE, ANNA, Forti, D., FAGGIANO, ELENA, Quarteroni, Alfio, Deparis, Simone, FEDELE, MARCO, DEDE', LUCA, QUARTERONI, ALFIO MARIA, Deparis, S., Forti, Davide   +9 more
core  

Bridging idealized and operational models: an explainable AI framework for Earth system emulators

npj Climate and Atmospheric Science
Computer models are indispensable tools for understanding the Earth system. While high-resolution operational models have achieved many successes, they exhibit persistent biases, particularly in simulating extreme events and statistical distributions. In
Pouria Behnoudfar, Charlotte Moser, Marc Bocquet, Sibo Cheng, Nan Chen   +4 more
doaj   +1 more source

A social inference model of idealization and devaluation.

Psychological Review
People often form polarized beliefs, imbuing objects (e.g., themselves or others) with unambiguously positive or negative qualities. In clinical settings, this is referred to as dichotomous thinking or "splitting" and is a feature of several psychiatric disorders. Here, we introduce a Bayesian model of splitting that parameterizes a tendency to rigidly
Giles W. Story, Ryan Smith, Michael Moutoussis, Isabel M. Berwian, Tobias Nolte, Edda Bilek, Jenifer Z. Siegel, Raymond J. Dolan   +7 more
openaire   +4 more sources

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

Medical therapy and imaging fixed-field alternating-gradient accelerator with realistic magnets

Physical Review Accelerators and Beams, 2017
NORMA is a design for a normal-conducting racetrack fixed-field alternating-gradient accelerator for protons from 50 to 350 MeV. In this article we show the development from an idealized lattice to a design implemented with field maps from rigorous two ...
S. Tygier, K. B. Marinov, R. B. Appleby, J. A. Clarke, J. M. Garland, H. L. Owen, B. J. A. Shepherd   +6 more
doaj   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh, Dalia Sriwi, Callie Saric, Tripti Singh, Christie M. Bartels, Shivani Garg   +5 more
wiley   +1 more source

Trajectories of Physical Function in Canadian Children With Juvenile Idiopathic Arthritis

Arthritis Care &Research, EarlyView.
Objective We describe trajectories of physical function in children newly diagnosed with juvenile idiopathic arthritis (JIA) and identify trajectories with persisting functional impairments and associated baseline characteristics. Methods We included patients enrolled in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry ...
Clare Cunningham, Meghan McPherson, Lillian Lim, Roberta A. Berard, Matthew Berkowitz, Jean‐Philippe Proulx‐Gauthier, Brian M. Feldman, Nicole Johnson, Dax G. Rumsey, Heinrike Schmeling, Lori B. Tucker, Thomas Loughin, Kristin M. Houghton, Jaime Guzman, for the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry Investigators, David A. Cabral, Gaëlle Chédeville, Ciarán M. Duffy, Kerstin Gerhold, Jaime Guzman, Linda Hiraki, Adam M. Huber, Heinrike Schmeling, Natalie J. Shiff, Lori B. Tucker, Julie Barsalou, Daniah Basodan, Michelle Batthish, Roberta A. Berard, Nicholas Blanchette, Gilles Boire, Roxana Bolaria, Alessandra Bruns, David A. Cabral, Sarah Campillo, Tania Cellucci, Mercedes Chan, Gaëlle Chédeville, Amieleena Chhabra, Julie Couture, Paul Dancey, Jean‐Jacques De Bruycker, Erkan Demirkaya, Muhammed Dhalla, Ciarán M. Duffy, Talal El Tal, Tommy Gerschman, Jaime Guzman, Liane Heale, Julie Herrington, Kristin M. Houghton, Adan M. Huber, Andrea Human, Nicole Johnson, Roman Jurencak, Bianca Lang, Claire LeBlanc, Lillian Lim, Lily S. H. Lim, Nadia Luca, Jeanine McColl, Tara McGrath, Tamara McMillan, Megan McPherson, Paivi Miettunen, Kimberly Morishita, Honyan Ng, Jonathan Park, Jean‐Philippe Proulx‐Gauthier, Johannes Roth, Evelyn Rozenblyum, Dax G. Rumsey, Heinrike Schmeling, Rosie Scuccimarri, Gordon Soon, Rebeka Stevenson, Elizabeth Stringer, Herman Tam, Lori B. Tucker, Marinka Twilt, Ruud H. J. Verstegen, Karen Watanabe Duffy   +81 more
wiley   +1 more source

Numerical simulations of human respiratory flows: a review

Discover Applied Sciences
This paper presents an overview of selected past and recent works on mathematical modeling and numerical simulations in respiratory fluid mechanics. The primary aim of this review is to systematically review, categorize and assess the state-of-the-art ...
Anna Lancmanová, Tomáš Bodnár
doaj   +1 more source