Results 31 to 40 of about 6,870,114 (256)
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Expediente – v. 14 jan./dez. 2020
Expediente do volume 14 (jan./dez. 2020) - Publicação contínua.
Revista IDeAS
doaj
Hair-brane Ideas on the Horizon [PDF]
We continue an examination of the microstate geometries program begun in arXiv:1409.6017, focussing on the role of branes that wrap the cycles which degenerate when a throat in the geometry deepens and a horizon forms.
Martinec, Emil J., Niehoff, Ben E.
core +2 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Expediente – v. 13 jan./dez. 2019
Expediente do volume 13 (jan./dez.
REVISTA IDEAS
doaj
Risk terrain modeling for monitoring illicit drugs markets across Bogota, Colombia
Colombia has gone from being a producer and exporter of illicit drugs to becoming a country where consumption also plays an important role. In Bogota, as result of specific policies adopted by the authorities that hit illicit drugs hot spots, the sale ...
José A. Escudero, Boris Ramírez
doaj +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source

