Results 41 to 50 of about 1,900,562 (304)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
An idea model for distributed Idea Management [PDF]
2010 IEEE International Technology Management Conference (ICE), 2010 Processes of Open Innovation and innovation in Living-Labs applying the co-creation paradigm do involve many participating innovators across different organisations and stakeholder groups. This is especially true when dealing with disruptive or radical innovations instead of incremental ones.
Duin, Heiko +3 more
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
, 1954 JULIAN MARIAS. Idea de la Metafísica, Colección Esquemas, Buenos Aires, 1954. / FRANCISCO ROMERO, Teoría del Hombre, Ed. Losada, Buenos Aires, 1953. / JUAN DAVID GARCÍA BACCA.- Antología del Pensamiento Filosófico Venezolano.
Ideas y, Valores
core +1 more source
Reaction of ethylene over a typical Fischer‐Tropsch synthesis Co/TiO2 catalyst
Engineering Reports, 2020 In order to identify the potential reaction paths of C2H4 and their product distribution in Fischer‐Tropsch synthesis (FTS), a series of experiments were designed over a Co/TiO2 catalyst in the absence of CO.
Yusheng Zhang +6 more
doaj +1 more source
Foro de debate: Estudiantes e investigación [PDF]
La Zaranda de Ideas, 2006 Durante el mes de Septiembre de 2005 se realizó en la ciudad de Córdoba el IX Congreso Nacional - II Latinoamericano de Estudiantes de Arqueología. El mismo fue organizado por estudiantes del Museo de Antropología, Facultad de Filosofía y Humanidades ...
La Zaranda de Ideas
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
, 2021 This paper attempts to expand on the scholarship surrounding the Jesuit strategy of cultural accommodation in China by Father Matteo Ricci by examining the influence of Chinese intellectual traditions on its inception and development. It incorporates the
Kearney, Finn
core
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Apresentação - volume 10 (2016)
Revista IDEAS, 2018 Apresentação da Revista IDeAS, volume 10, número 1-2, de 2016, publicado em 15 de junho de 2018.
REVISTA IDEAS
doaj