Results 61 to 70 of about 1,025,509 (265)
Personal Utopia: The “Good Life” in Popular Religion and Literature in Contemporary Sweden
Culture Unbound: Journal of Current Cultural Research, 2018 This article examines the discourse of the “good life” in popular religion and literature in contemporary Sweden. The results indicate thnew spiritual movements (e.g.
Daniel Enstedt, Kristina Hermansson
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Idea Generation and the Quality of the Best Idea
Management Science, 2009 In a wide variety of settings, organizations generate a number of possible solutions to a problem—ideas—and then select a few for further development. We examine the effectiveness of two group structures for such tasks—the team structure, in which the group works together in time and space, and the hybrid structure, in which individuals first work ...
Karan Girotra +2 more
openaire +4 more sources
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Ideas y Valores, 1953 Nuevos libros de Heidegger / Actividad filosófica en Friburgo (Alemania) / Trabajos de Filosofía / Adolfo Carpio / Publicaciones recientes / Tradición y Tarea / Congreso de Filosofía / Carta de Madrid / Conferencias del Profesor Ernesto Grassi ...
. Ideas y Valores
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Ideas y Valores, 1973 Louis Althusser / Juergen Habermas / Jean - Toussaint Desanti / Paul Ricoeur / Alfred Schmidt / Noël Mouloud / Ramon Garzón / Jorge Aurelio Diaz / Freddy Téllez / Fernando Urbina / Breve bibliografía sobre el tema de la ...
. Ideas y Valores
doaj
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source