Results 31 to 40 of about 66,185 (233)

Identifiability of mathematical models in medical biology

open access: yesВавиловский журнал генетики и селекции, 2016
Analysis of biological data is a key topic in bioinformatics, computational genomics, molecular modeling and systems biology. The methods covered in this article could reduce the cost of experiments for biological data.
S. I. Kabanikhin   +3 more
doaj   +1 more source

Uncovering Multi-Site Identifiability Based on Resting-State Functional Connectomes

open access: yes, 2019
Multi-site studies are becoming important to increase statistical power, enhance generalizability, and to improve the likelihood of pooling relevant subgroups together activities.
Amico, Enrico   +4 more
core   +1 more source

Parameter identifiability in a class of random graph mixture models [PDF]

open access: yes, 2010
We prove identifiability of parameters for a broad class of random graph mixture models. These models are characterized by a partition of the set of graph nodes into latent (unobservable) groups.
Airoldi   +33 more
core   +3 more sources

Structural identifiability of biomolecular controller motifs with and without flow measurements as model output.

open access: yesPLoS Computational Biology, 2023
Controller motifs are simple biomolecular reaction networks with negative feedback. They can explain how regulatory function is achieved and are often used as building blocks in mathematical models of biological systems.
Eivind S Haus   +2 more
doaj   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle   +5 more
wiley   +1 more source

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan   +6 more
wiley   +1 more source

On the dimension of contact loci and the identifiability of tensors

open access: yes, 2017
Let $X\subset \mathbb{P}^r$ be an integral and non-degenerate variety. Set $n:= \dim (X)$.
Ballico, Edoardo   +2 more
core   +1 more source

The Role of Invasive Procedures in the Treatment of Complicated Gastrointestinal Graft‐Versus‐Host Disease in Pediatric Patients

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Gastrointestinal graft‐versus‐host disease (GI GVHD) following hematopoietic stem cell transplant is typically managed with medical therapy, but surgery and angioembolization may be warranted in selected cases with life‐threatening complications.
Gaia Brunetti   +12 more
wiley   +1 more source

Determining Structurally Identifiable Parameter Combinations Using Subset Profiling [PDF]

open access: yes, 2013
Identifiability is a necessary condition for successful parameter estimation of dynamic system models. A major component of identifiability analysis is determining the identifiable parameter combinations, the functional forms for the dependencies between
Eisenberg, Marisa C.   +1 more
core  

Blinatumomab Utilization in Pediatric B‐Cell Acute Lymphoblastic Leukemia: Experience From the Mountain West

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego   +10 more
wiley   +1 more source

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