Results 41 to 50 of about 30,482 (307)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
Understanding cyberhate: Social competition and social creativity in on-line White-supremacist groups [PDF]
, 2005 This study investigated the self-enhancement strategies used by online White supremacist groups. In accordance with social identity theory, we proposed that White supremacist groups, in perceiving themselves as members of a high-status, impermeable group
McGarty, Craig +11 more
core +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Advanced SciencePractical identifiability is a fundamental challenge in the data‐driven modeling of biological systems, as many model parameters cannot be directly measured and must be estimated from experimental data.
Shun Wang, Wenrui Hao
doaj +1 more source
The Annals of Applied ProbabilityA group of players are supposed to follow a prescribed profile of strategies. If they follow this profile, they will reach a given target. We show that if the target is not reached because some player deviates, then an outside observer can identify the deviator. We also construct identification methods in two nontrivial cases.
Noga Alon +4 more
openaire +4 more sources
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Classical structural identifiability methodology applied to low-dimensional dynamic systems in receptor theory [PDF]
, 2023 Mathematical modelling has become a key tool in pharmacological analysis, towards understanding dynamics of cell signalling and quantifying ligand-receptor interactions.
Rottschäfer, Vivi +5 more
core +1 more source
PLoS Computational Biology, 2023 Controller motifs are simple biomolecular reaction networks with negative feedback. They can explain how regulatory function is achieved and are often used as building blocks in mathematical models of biological systems.
Eivind S Haus +2 more
doaj +1 more source