Results 41 to 50 of about 15,093 (264)
The Linacre Quarterly, 2017 Defenders of human, embryonic, destructive stem-cell research and early abortion typically argue for their position by showing that you and I do not come into existence at conception but rather at some point after. Eugene Mills has provided an ingenious argument that you and I could not have come into existence at conception.
openaire +2 more sources
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
When It Counts—Econometric Identification of the Basic Factor Model Based on GLT Structures
Econometrics, 2023 Despite the popularity of factor models with simple loading matrices, little attention has been given to formally address the identifiability of these models beyond standard rotation-based identification such as the positive lower triangular (PLT ...
Sylvia Frühwirth-Schnatter +2 more
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Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
An Objective Measure of Distributional Estimability as Applied to the Phase-Type Aging Model
RisksThe phase-type aging model (PTAM) is a class of Coxian-type Markovian models that can provide a quantitative description of the effects of various aging characteristics.
Cong Nie, Xiaoming Liu, Serge B. Provost
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
CPT: Pharmacometrics & Systems PharmacologyParameter identifiability methods assess whether the parameters of a model are uniquely determined by the observations. While the success of a model fit can provide some information on this, it can be valuable to determine identifiability before any fit ...
Martijn vanNoort, Martijn Ruppert
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Space-Time Coded MC-CDMA: Blind Channel Estimation, Identifiability, and Receiver Design
EURASIP Journal on Advances in Signal Processing, 2002 Integrating the strengths of multicarrier (MC) modulation and code division multiple access (CDMA), MC-CDMA systems are of great interest for future broadband transmissions. This paper considers the problem of channel identification and signal combining/
Li Hongbin, Sun Wei
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Parameter Identifiability of Discrete Bayesian Networks with Hidden Variables
Journal of Causal Inference, 2015 Identifiability of parameters is an essential property for a statistical model to be useful in most settings. However, establishing parameter identifiability for Bayesian networks with hidden variables remains challenging.
Allman Elizabeth S. +3 more
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Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source