Results 171 to 180 of about 5,701,500 (381)

Meloidogyne graminicola—A Threat to Rice Production: Review Update on Distribution, Biology, Identification, and Management [PDF]

, 2021
Leidy Rusinque, Carla Maleita, Isabel Abrantes, Juan E. Palomares‐Rius, Maria L. Inácio   +4 more
openalex   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

How New Insights in the Biology of Brain Metastases May Lead to the Identification of New Effective Medical Therapies [PDF]

, 2012
Brunilde Gril, Thomas Bachelot, Gilles Romieu, Claire Cropet, Mario Campone, Véronique Dièras, Mónica Jiménez, Florence Dalenc, Émilie Le Rhun, C. Labbé-Devilliers, Frank J. Lagerwaard   +10 more
openalex   +1 more source

A network-biology approach for identification of key genes and pathways involved in malignant peritoneal mesothelioma [PDF]

, 2021
A. M. U. B. Mahfuz, A. M. Zubair-Bin-Mahfuj, Dibya Joti Podder   +2 more
openalex   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Erratum to: Identification of uncultured bacteria tightly associated with the intestine of the earthworm Lumbricus rubellus (Lumbricidae; Oligochaeta) [Soil Biology & Biochem. 35(12):1547–55]

, 2004
David R. Singleton, Paul F. Hendrix, David C. Coleman, William B. Whitman   +3 more
openalex   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Benefits and risks associated with genetically modified food products

Annals of Agricultural and Environmental Medicine, 2013
Scientists employing methods of genetic engineering have developed a new group of living organisms, termed ‘modified organisms’, which found application in, among others, medicine, the pharmaceutical industry and food distribution.
Marta Kramkowska, Teresa Grzelak, Krystyna Czyżewska, Ewa Mierzejewska, Renata Welc-Faleciak, Andrzej Bohatyrewicz, Aleksandra Lanocha, Rafał Celiński, Agata Bielawska-Drózd, Justyna Joniec, Marcin Kołodziej, Grzegorz Graniak, Mariusz Goniewicz, Leszek Kubiak   +13 more
doaj  

Understanding foot-and-mouth disease virus transmission biology: identification of the indicators of infectiousness [PDF]

, 2013
Margo Chase‐Topping, Ian Handel, B. Bankowski, Nicholas Juleff, Debi Gibson, Sarah J. Cox, Miriam Windsor, Elizabeth Reid, Claudia Doel, Richard Howey, Paul V. Barnett, Mark Woolhouse, Bryan Charleston   +12 more
openalex   +1 more source