Results 51 to 60 of about 4,350,325 (326)

Potentials of single‐cell biology in identification and validation of disease biomarkers

open access: yesJournal of Cellular and Molecular Medicine, 2016
Single‐cell biology is considered a new approach to identify and validate disease‐specific biomarkers. However, the concern raised by clinicians is how to apply single‐cell measurements for clinical practice, translate the message of single‐cell systems ...
F. Niu   +4 more
semanticscholar   +1 more source

Between Droughts and Floods: The Seasonal Response of Freshwater Snails in Artificial Reservoirs in the Brazilian Semiarid Region

open access: yesPopulation Ecology, EarlyView.
We investigate the seasonal dynamics of two freshwater snails, Biomphalaria straminea and Melanoides tuberculata, in artificial reservoirs of the Brazilian semiarid region. Despite regulated hydrology, B. straminea exhibited strong seasonal fluctuations associated with dry periods, while M. tuberculata maintained stable populations throughout the year,
Lucas Henrique Sousa da Silva   +6 more
wiley   +1 more source

Comparison between Conventional Blind Injections and Ultrasound-Guided Injections of Botulinum Toxin Type A into the Masseter: A Clinical Trial

open access: yesToxins, 2020
The aim of the study was to propose a more efficient and safer botulinum toxin type A (BoNT-A) injection method for the masseter by comparing the conventional blind injection and a novel ultrasonography (US)-guided injection technique in a clinical trial.
Hyungkyu Bae   +5 more
doaj   +1 more source

Moving in the Dark: Enlightening the Spatial Population Ecology of European Cave Salamanders

open access: yesPopulation Ecology, EarlyView.
We assessed individual interactions, movement ecology and activity patterns of a subterranean population of Speleomantes strinatii, applying spatial capture–recapture modeling to a photographic dataset of 104 individuals. ABSTRACT Space use and movement are fundamental aspects of organisms' ecology, mirroring individual fitness, behavior, and life ...
Giacomo Rosa   +2 more
wiley   +1 more source

Mass spectrometric monitoring of interfacial photoelectron transfer and imaging of active crystalline facets of semiconductors

open access: yesNature Communications, 2017
Monitoring interfacial electron transfer in photocatalytic systems is fundamentally important but experimentally challenging. Here the authors use mass spectrometry to detect and monitor intermediates formed through photoelectron transfer and to image ...
Hongying Zhong   +8 more
doaj   +1 more source

Infection Models for Pine Wilt Disease on the Basis of Vector Behaviors

open access: yesPopulation Ecology, EarlyView.
Infection models for pine wilt disease without vector density were built to estimate the transmission coefficient of the pathogenic nematode. The models successfully simulated the annual change in the density of infected trees for four pine stands. ABSTRACT Pine wilt disease is caused by the pinewood nematode (Bursaphelenchus xylophilus Steiner et ...
Katsumi Togashi
wiley   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Ideal Injection Points for Botulinum Neurotoxin for Pectoralis Minor Syndrome: A Cadaveric Study

open access: yesToxins, 2023
Pectoralis Minor Syndrome (PMS) causes significant discomfort due to the compression of the neurovascular bundle within the retropectoralis minor space.
Ji-Hyun Lee   +5 more
doaj   +1 more source

Identification of Predictive Biomarkers for Cytokine Release Syndrome after Chimeric Antigen Receptor T-cell Therapy for Acute Lymphoblastic Leukemia.

open access: yesCancer Discovery, 2016
UNLABELLED Chimeric antigen receptor (CAR)-modified T cells with anti-CD19 specificity are a highly effective novel immune therapy for relapsed/refractory acute lymphoblastic leukemia.
D. Teachey   +26 more
semanticscholar   +1 more source

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