Results 61 to 70 of about 5,717,926 (305)

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko, Segev Gabay, Jonathan Roth, Amit Ringel, Rina Dvir, Shlomi Constantini   +5 more
wiley   +1 more source

Bone and Soft Tissue Neoplasms in Infants Versus Older Children: A Report From the Cancer in Young People in Canada Program

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.
Samuel Sassine, Hallie Coltin, Maria Kondyli, Monia Marzouki, Nicolas Prud'homme, Nida Usmani, Rebecca J. Deyell, Lesleigh Abbott, Tony H. Truong, Sapna Oberoi, Ketan Kulkarni, Josée Brossard, Lynette Bowes, Paul Gibson, Sarah McKillop, Roona Sinha, Lillian Sung, Catherine Vezina, Laura Wheaton, Alexandra P. Zorzi, Marie‐Claude Pelland‐Marcotte, Thai Hoa Tran   +21 more
wiley   +1 more source

Neurocognitive, School‐Based, and Quality of Life Outcomes for Youth With Sickle Cell Disease and Thalassemia: A Scoping Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT The medical burdens of sickle cell disease (SCD) and transfusion‐dependent β‐thalassemia (TDT) are chronic and cumulative, even in children. Yet the effects expand beyond medications and healthcare visits due to their impacts on school attendance, academic performance, and peer engagement.
Mary Ann Etling, Hakim Tokhi, Alexander A. Boucher   +2 more
wiley   +1 more source

Anatomical Guidelines and Technical Tips for Neck Aesthetics with Botulinum Toxin

Archives of Plastic Surgery
Botulinum toxin can be used for various purposes to enhance neck aesthetics, addressing concerns such as platysmal bands, optimizing the cervicomental angle, preventing worsening of horizontal neckline and decolletage lines during aging, submandibular ...
Hyewon Hu, Soo-Bin Kim, Jovian Wan, Lisa Kwin Wah Chan, Alvin Kar Wai Lee, Olena Sydorchuk, Arash Jalali, Mariana César Corrêa, Jong-Seo Kim, Kyu-Ho Yi   +9 more
doaj   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

Functional Translational Readthrough: A Systems Biology Perspective.

, 2016
Translational readthrough (TR) has come into renewed focus because systems biology approaches have identified the first human genes undergoing functional translational readthrough (FTR).
Fabian Schueren, Schueren, Fabian, Sven Thoms, Thoms, Sven   +3 more
core   +1 more source

Drug target identification through systems biology

Drug Discovery Today: Technologies, 2015
To rationalise drug target selection, we should understand the role of putative targets in biological pathways quantitatively. We review here how experimental and computational network-based approaches can aid more rational drug target selection and illustrate this with results obtained for microbes and for cancer.
Jurgen R. Haanstra, Barbara M. Bakker
openaire   +3 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

The S-Star Trial Bioinformatics course: An on-line learning success

, 2003
10.1002/bmb.2003.494031010160Biochemistry and Molecular Biology Education31120 ...
Jan‐Olov Höög, Lim, Y.P., Höög, J.-O., Subbiah, S., Phyllis Gardner, Hide, W., Shoba Ranganathan, Ranganathan, S., Winston Hide, Andersson, S., Yun Ping Lim, Anthony S. Weiss, Gardner, P., Tan, T.W., Siv Andersson, Weiss, A.S., Subramanian Subbiah, Tin Wee Tan, Höög, JO, Tan, TW, Subbiah, S, Andersson, S, Hide, W, Lim, YP, Weiss, AS, Gardner, P, Ranganathan, S   +26 more
core   +1 more source

Networks in Biology – From Identification, Analysis to Interpretation [PDF]

, 2009
Over the last decade networks has become a unifying language in biology. Yet we are only in the beginning of understanding their significance for biology and their medical applications. I will talk about the diversity of biological networks composed either of genes, proteins, metabolites, or cells and the associated methods for finding these graphs in ...
openaire   +2 more sources