Results 11 to 20 of about 1,706,119 (263)

Protective Effect of Curcumin on Acrylamide-Induced Hepatic and Renal Impairment in Rats: Involvement of CYP2E1

open access: yesNatural Product Communications, 2020
As a chemical extensively used in industrial areas and formed during heating of carbohydrate-rich foods and tobacco, acrylamide (ACR) has been demonstrated to exert a variety of systemic toxic effects including hepatotoxicity and nephrotoxicity.
Rui Sun   +4 more
doaj   +1 more source

Risks of benzalkonium chlorides as emerging contaminants in the environment and possible control strategies from the perspective of ecopharmacovigilance

open access: yesEcotoxicology and Environmental Safety, 2023
An unprecedented increase in the use of disinfection products triggered by the coronavirus disease 2019 (COVID-19) pandemic is resulting in aggravating environmental loads of disinfectants as emerging contaminants, which has been considered a cause for ...
Mengfan Liao   +4 more
doaj   +1 more source

Analysis of Five Mushroom Toxins in Blood by UPLC-HRMS

open access: yesFayixue Zazhi, 2021
ObjectiveTo develop a method for the simultaneous and rapid detection of five mushroom toxins (α-amanitin, phallacidin, muscimol, muscarine and psilocin) in blood by ultra-high performance liquid chromatography-high resolution mass spectrometry (UPLC ...
LIU Wen-qiao   +8 more
doaj   +1 more source

TLR4 signaling in the development of colitis-associated cancer and its possible interplay with microRNA-155

open access: yesCell Communication and Signaling, 2021
Ulcerative colitis (UC) has closely been associated with an increased risk of colorectal cancer. However, the exact mechanisms underlying colitis-associated cancer (CAC) development remain unclear.
Jie Guo, Mengfan Liao, Jun Wang
doaj   +1 more source

CCK1R2R-/- ameliorates myocardial damage caused by unpredictable stress via altering fatty acid metabolism

open access: yesStress, 2023
The heart is the main organ of the circulatory system and requires fatty acids to maintain its activity. Stress is a contributor to aggravating cardiovascular diseases and even death, and exacerbates the abnormal lipid metabolism.
Zhi-Hua Zhang   +6 more
doaj   +1 more source

New Advances, Challenges and Opportunities in Forensic Applications of Microbiomics

open access: yesFayixue Zazhi, 2022
The succession of microbiota is closely associated with several essential factors, including race, sex, health condition, lifestyle, postmortem interval, etc., and it has great potential application value in forensic medicine.
LEI Fan-zhang   +4 more
doaj   +1 more source

Protective effect of ethyl acetate fraction from Semen sojae germinatum, the processed sprout of Chinese black soybean, on rat experimental osteoarthritis

open access: yesBMC Complementary Medicine and Therapies, 2020
Background Our previous in vitro study reported that the ethyl acetate fraction (EAF) of Semen sojae germinatum (SSG), the processed sprout of Chinese black soybean, possessed the potent anti-inflammatory and chondroprotective properties.
Jun Wang   +4 more
doaj   +1 more source

Forensic Features and Genetic Structure Analyses of the Beijing Han Nationality Disclosed by a Self-Developed Panel Containing a Series of Ancestry Informative Deletion/Insertion Polymorphism Loci

open access: yesFrontiers in Ecology and Evolution, 2022
The utilization of the ancestry informative markers to disclose the ancestral composition of a certain population and explore the genetic affinities between diverse populations is beneficial to inferring the biogeographic ancestry of unknown individuals ...
Hui Xu   +8 more
doaj   +1 more source

Determination of barbiturates in hair samples by using a validated UHPLC-HRMS method: application in investigation of drug-facilitated sexual assault

open access: yesForensic Sciences Research, 2019
In recent years, benzodiazepines and benzodiazepine-like drugs are the most common substances associated with drug-facilitated sexual assaults (DFSA); however, barbiturates are also detected occasionally.
Di Wen   +8 more
doaj   +1 more source

Shuxuening injection, derived from Ginkgo biloba leaf, induced pseudo-allergic reactions through hyperactivation of mTOR

open access: yesPharmaceutical Biology, 2020
Context Shuxuening injection (SXNI), derived from the leaf of Ginkgo biloba L. (Ginkgoaceae), is widely used to treat cardio-cerebral vascular system related disease due to the efficacy of dilating the blood vessels and improving the function of ...
Lianmei Wang   +13 more
doaj   +1 more source

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