Results 131 to 140 of about 453,327 (300)

Administering the Code of Good Manufacturing Practice for prescription medicines [PDF]

open access: yes, 2014
This audit assessed the effectiveness of the Therapeutic Goods Administration’s application of the Code of Good Manufacturing Practice for prescription medicines.

core  

MAGECODE: Machine-Generated Code Detection Method Using Large Language Models

open access: yesIEEE Access
The widespread use of virtual assistants (e.g., GPT4 and Gemini, etc.) by students in their academic assignments raises concerns about academic integrity.
Hung Pham   +5 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

AICodeReview: Advancing code quality with AI-enhanced reviews

open access: yesSoftwareX
This paper presents a research investigation into the application of Artificial Intelligence (AI) within code review processes, aiming to enhance the quality and efficiency of this critical activity.
Yonatha Almeida   +7 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Identifying software vulnerabilities via code representation learning [PDF]

open access: yes
In the era of big code, the proliferation of software applications has led to a corresponding increase in unidentified vulnerabilities, necessitating early detection during development to avoid potential disruptions and security risks post-deployment ...
Wu, Bozhi
core   +1 more source

CODE MIXING FOUND IN BUKAN EMPAT MATA PROGRAM ON TRANS 7 TELEVISION CHANNEL

open access: yesJEELS (Journal of English Education and Linguistics Studies), 2015
This study is aimed to find the kinds of code mixing and to know which kinds of code mixing are dominantly used in Bukan Empat Mata Program on TRANS 7 Television channel. Descriptive qualitative method is used in this study.
Fitria Nur Hamidah
doaj  

On cages admitting identifying codes

open access: yesEuropean Journal of Combinatorics, 2008
The motivation for identifying codes, introduced in [IEEE Trans. Inf. Theory 44, No. 2, 599--611 (1998; Zbl 1105.94342)] by \textit{M. G. Karpovsky}, \textit{K. Chakrabarty} and \textit{L. B. Levitin}, comes from finding faulty processors in a multiprocessor system.
openaire   +2 more sources

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

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