Results 121 to 130 of about 453,327 (300)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

A Type of Coding Method of IPv6 Flow Label with QoS Support

Dianxin kexue, 2013
By redefining the reserved CU bits in IPv6 header traffic class field and the structured code of IPv6 flow label,the region information, application information, port number or other information were defined.
Yangchun Li, Weiwei Feng, Jie Zou, Jinghua Tan   +3 more
doaj   +2 more sources

Code Status Transitions of Patients with Aneurysmal Subarachnoid Hemorrhage in the Intensive Care Unit

Palliative Medicine Reports
Background: Aneurysmal subarachnoid hemorrhage (aSAH) carries high mortality rates and often requires critical family decisions about code status when complications occur.
Min-I Su, Chia-Ying Hsiao, Jui-Chu Ma, Che-Ming Chang   +3 more
doaj   +1 more source

Progress on Self Identifying Codes

CoRR
The concept of an identifying code for a graph was introduced by Karpovsky, Chakrabarty, and Levitin in 1998 as the problem of covering the vertices of a graph such that we can uniquely identify any vertex in the graph by examining the vertices that cover it.
Devin C. Jean, Suk Seo
openaire   +2 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Identifying Sentiments in Algerian Code-switched User-generated Comments [PDF]

, 2020
We present in this paper our work on Algerian language, an under-resourced North African colloquial Arabic variety, for which we built a comparably large corpus of more than 36,000 code-switched user-generated comments annotated for sentiments.
Touileb, Samia, Adouane, Wafia,, Bernardy, Jean-Philippe,   +2 more
core  

Almost optimal geometrically local quantum LDPC codes in any dimension

Nature Communications
Geometrically local quantum codes, comprised of qubits and checks embedded in $${{\mathbb{R}}}^{D}$$ R D with local check operators, have been a subject of significant interest.
Xingjian Li, Ting-Chun Lin, Adam Wills, Min-Hsiu Hsieh   +3 more
doaj   +1 more source

The Use of Code-Mixing and Code-Switching: Challenge Identification in Language Online Mass Media

IJOTL-TL (Indonesian Journal of Language Teaching and Linguistics)
This study is aimed at investigating types of code-mixing and code-switching as challenges in language identification in online mass media. Journalists mostly mix language to emphasize particular topics and to reiterate them as well.
Ratna Susanti, Haryanto Haryanto , Iswahyu Pranawukir, Muh Safar, Indra Tjahyadi   +4 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source