Results 111 to 120 of about 3,507,644 (308)

SATT: Tailoring code metric thresholds for different software architectures

, 2016
Code metric analysis is a well-known approach for assessing the quality of a software system. However, current tools and techniques do not take the system architecture (e.g., MVC, Android) into account. This means that all classes are assessed similarly,
Treude, Christoph (author), van Deursen, A. (author), Andy Zaidman, Treude, C., Treude, Christoph, Zaidman, A., Gerosa, Marco Aurélio (author), Marco Aurelio Gerosa, Mauricio Aniche, Zaidman, A.E. (author), ZAIDMAN, Andy, Aniche, Maurício (author), Deursen, A., Christoph Treude, VAN DEURSEN, Arie, Aniche, M., Zaidman, A.E., Gerosa, Marco Aurélio, Arie Van Deursen, Aniche, Maurício, Gerosa, M., van Deursen, A.   +21 more
core   +2 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

code

, 2020
code
Yifan Zhang (7874882)
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Software-Architecture Recovery from Machine Code [PDF]

, 2013
In this paper, we present a tool, called Lego, which recovers object-oriented software architecture from stripped binaries. Lego takes a stripped binary as input, and uses information obtained from dynamic analysis to (i) group the functions in the ...
Srinivasan, Venkatesh Karthik, Reps, Thomas   +1 more
core  

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

A Developer-Oriented Framework for Assessing Power Consumption in Mobile Applications: Android Energy Smells Case Study

Sensors
Currently, people spend a lot of time using their mobile devices. With such ubiquity of mobile devices in our daily life, battery capacity and quality are of utmost importance.
Claudiu Groza, Apostol Dumitru-Cristian, Marius Marcu, Razvan Bogdan   +3 more
doaj   +1 more source

Sentiment Analysis of Code-Mixed Text: A Comprehensive Review [PDF]

Journal of Universal Computer Science
Sentiment Analysis is the task of identifying and extracting the opinion expressed in a text to determine the writer's perception of an entity.
Anne Perera, Amitha Caldera
doaj   +3 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source