Results 111 to 120 of about 453,327 (300)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

The Complexity of the Identifying Code Problem in Restricted Graph Classes [PDF]

, 2013
International audienceAn identifying code is a subset of vertices of a graph such that each vertex is uniquely determined by its nonempty neighbourhood within the identifying code. We study the associated computational prob- lem Minimum Identifying Code,
Florent Foucaud, Foucaud, Florent
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Study of Identifying Code Polyhedra for Some Families of Split Graphs [PDF]

, 2014
International audienceThe identifying code problem is a newly emerging search problem, challenging both from a theoretical and a computational point of view, even for special graphs like bipartite graphs and split graphs.
Wagler, Annegret, K, Annegret Wagler, Argiroffo, Gabriela, Gabriela Argiroffo, Bianchi, Silvia, Silvia Bianchi   +5 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Validation of ICD‐10 Consensus Code Set for Cirrhosis Detection Using Electronic Health Records in an Asian Population

JGH Open
Background Systematic identification of patients with cirrhosis through electronic healthcare records (EHRs) using ICD‐10 codes is essential for epidemiological research but is prone to discrepancies.
Jason Pik‐Eu Chang, Hong‐Yi Lin, Pooi‐Ling Loi, Jeanette Pei‐Xuan Ng, Marianne De Roza, Rahul Kumar, Hiang‐Keat Tan, Chanda Kendra Ho, Wei‐Quan Teo, Amber Hwa Hwa Chung, Prema Raj   +10 more
doaj   +1 more source

Sentiment Analysis of Code-Mixed Text: A Comprehensive Review [PDF]

Journal of Universal Computer Science
Sentiment Analysis is the task of identifying and extracting the opinion expressed in a text to determine the writer's perception of an entity.
Anne Perera, Amitha Caldera
doaj   +3 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

A Process for Identifying Changes When Source Code is Not Available [PDF]

, 2005
Various regression test selection techniques have been developed and shown to improve fault detection effectiveness. The majority of these test selection techniques rely on access to source code for change identification.
Brian Robinson, Laurie Williams, Jiang Zheng, Karen Smiley   +3 more
core   +1 more source

A Developer-Oriented Framework for Assessing Power Consumption in Mobile Applications: Android Energy Smells Case Study

Sensors
Currently, people spend a lot of time using their mobile devices. With such ubiquity of mobile devices in our daily life, battery capacity and quality are of utmost importance.
Claudiu Groza, Apostol Dumitru-Cristian, Marius Marcu, Razvan Bogdan   +3 more
doaj   +1 more source